Can MRI spot radiation damage in the mouth? new study aims to find out
NCT ID NCT06586892
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study will test whether special MRI scans can accurately detect and track damage to the mouth and jaw caused by radiation therapy for head and neck cancers. Researchers will enroll 300 adults undergoing radiation, with some receiving additional MRI scans before and after treatment. The goal is to validate MRI as a reliable tool for diagnosing osteoradionecrosis, a serious complication, and to improve monitoring of soft tissue health.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MRI scan
What this could lead to
If successful, this could provide a reliable way to detect and monitor mouth and jaw damage from radiation, helping doctors treat it earlier.
What could go wrong
This is an early validation study, not a treatment trial. The MRI method may not prove accurate enough for routine use, and results may not apply to all patients.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The University of Texas M. D. Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact