Simple blood test may spot ovarian cancer sooner

NCT ID NCT00539162

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether combining the standard CA125 blood test with other tumor markers can help detect ovarian cancer earlier in women who are at low risk. Researchers will track 8,000 postmenopausal women over time, repeating blood tests and sometimes ultrasound if markers rise. The goal is to improve early detection, but this is an observational study, not a treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a simple blood test that catches ovarian cancer earlier, when it's easier to treat.

What could go wrong

This is an observational study, not a treatment trial. It may not prove that early detection saves lives, and false alarms could cause unnecessary worry or procedures.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ovarian cancer prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-••••

Locations

  • Carol G. Simon Cancer Center / Atlantic Health

    RECRUITING

    Morristown, New Jersey, 07962, United States

  • John Stoddard Cancer Center

    RECRUITING

    Des Moines, Iowa, 50309, United States

  • Sylvester Comprehensive Cancer Center, Univ of Miami Miller School of Medicine

    RECRUITING

    Miami, Florida, 33136, United States

    Contact

  • The University of Texas at Austin

    ACTIVE_NOT_RECRUITING

    Austin, Texas, 78712, United States

  • UT Health Science Center San Antonio

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact

  • University of Minnesota

    RECRUITING

    Minneapolis, Minnesota, 55454, United States

    Contact

  • University of Oklahoma Health Sciences Center

    RECRUITING

    Oklahoma City, Oklahoma, 73104, United States

    Contact

  • University of Rochester Medical Center

    RECRUITING

    Rochester, New York, 14642, United States

    Contact

  • University of Texas (UT) Southwestern Medical Center

    ACTIVE_NOT_RECRUITING

    Dallas, Texas, 75390, United States

  • University of Texas MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

  • Women's Hospital of Texas, Obstetrics and Gynecology Associates (OGA)

    RECRUITING

    Houston, Texas, 77054, United States

  • Women's and Infant's Hospital

    RECRUITING

    Providence, Rhode Island, 02905, United States