Could prebiotic snacks boost melanoma treatment?

NCT ID NCT06548789

Recruiting now Disease control Sponsor: M.D. Anderson Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a prebiotic-rich diet to standard immunotherapy before surgery can improve immune response in people with melanoma. About 35 adults with resectable melanoma will receive prebiotic snack packs and diet counseling alongside their usual treatment. The main goal is to see if patients can stick with the diet and how it affects their gut microbiome and treatment outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Prebiotic snack packouts and dietary counseling
What this could lead to: If it works, this could show that adding prebiotic foods to standard immunotherapy improves treatment response in melanoma patients.
What could go wrong: This is a small, early-phase trial with only 35 participants, so results may not apply to everyone. The diet may be hard to follow, and it's unclear if it will meaningfully improve outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cutaneous melanoma melanoma mucosal melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MELANOMA

Contacts and locations

Locations

MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States

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