Promising drug cocktail targets tough blood cancers in kids
NCT ID NCT06561074
First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 2 times
Summary
This study tests whether a combination of three drugs—calaspargase pegol-mknl, decitabine, and venetoclax—can help control relapsed or treatment-resistant T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LLy) in patients aged 1 month to 21 years. The goal is to see if the treatment reduces cancer burden and to monitor side effects. About 22 participants will be enrolled at M.D. Anderson Cancer Center.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77090, United States
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Other studies related to the condition(s) this trial covers.
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