Engineered immune cells take aim at stubborn blood cancers

NCT ID NCT04033302

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a new type of immunotherapy called CAR-T cells that are designed to recognize and attack cancer cells carrying a protein called CD7. It includes people with several blood cancers, such as T-cell acute lymphoblastic leukemia and acute myeloid leukemia. The goal is to see if the treatment is safe and can shrink tumors.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
CD7-specific CAR-T cells
What this could lead to
If successful, this could offer a new treatment option for people with hard-to-treat blood cancers that express the CD7 protein.
What could go wrong
This is an early-phase trial with only 30 participants, so results may not apply broadly. CAR-T therapy can cause severe side effects like cytokine release syndrome.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Shenzhen Geno-immune Medical Institute

    RECRUITING

    Shenzhen, Guangdong, 518000, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.