New drug combo aims to control aggressive blood cancers

NCT ID NCT05365035

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 23 times

Summary

This study tests a combination of four drugs (cladribine, cytarabine, venetoclax, and azacitidine) to see if it can help control higher-risk myelodysplastic syndrome (MDS) or chronic myelomonocytic leukemia (CMML) that has not responded to standard treatments. About 60 adults aged 18 and older will participate. The goal is to improve overall survival by alternating two different drug combinations over several cycles.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.