Brain scan showdown: spotting fake tumor growth

NCT ID NCT06199479

Recruiting now Diagnosis Sponsor: M.D. Anderson Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether advanced MRI and CT scans can tell the difference between a brain tumor that is actually growing (true progression) and one that only looks like it is growing after treatment (pseudoprogression). About 25 adults who have had brain tumor treatment and now show a suspicious spot on scans will get additional imaging and a standard biopsy. The goal is to see if the scans alone can give the right answer, potentially avoiding unnecessary procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors avoid unnecessary biopsies and treatments by accurately identifying when a brain tumor is not actually progressing.
What could go wrong: This is a very small, early-phase study (25 people) focused on imaging accuracy, not treatment. The methods may not work for all patients or tumor types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BRAIN MALIGNANCIES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

brain cancer glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRAIN MALIGNANCIES PSEUDOPROGRESSION

Contacts and locations

Locations

MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.