Can MRI predict radiation side effects before they happen?

NCT ID NCT04265430

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study uses repeated MRI scans after radiation therapy to see if they can predict normal tissue damage, like bone death (osteoradionecrosis), in patients with oral cavity or skull base tumors. Researchers will track changes in imaging over time and link them to radiation dose. The goal is to find early warning signs of injury, which could help doctors adjust treatment or intervene sooner.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors predict and prevent radiation-induced bone damage in cancer patients, improving long-term quality of life.

What could go wrong

This is an observational imaging study, not a treatment trial. It may not lead to direct patient benefits, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OSTEORADIONECROSIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Mouth Neoplasms oral cavity cancer oropharynx cancer osteonecrosis of the jaw osteoradionecrosis skull base neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-••••

    Contact