New combo therapy targets tough blood cancers with two genetic flaws

NCT ID NCT07032727

First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 26 times

Summary

This study tests whether combining olutasidenib with other targeted drugs is safe and tolerable for people whose blood cancer (like AML or MDS) has returned or not responded to treatment. Participants must have both an IDH1 mutation and another mutation in a signaling pathway gene. The goal is to find better options for these hard-to-treat cancers.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.