Common painkillers may block colon cancer in high-risk group

NCT ID NCT05411718

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 24 times

Summary

This study tests whether naproxen or aspirin can increase immune cells in the colon to prevent cancer in people with Lynch syndrome, a genetic condition that raises cancer risk. About 40 participants will take one of these drugs or a placebo for a short time. Researchers will measure changes in T cells and other immune markers in colon tissue.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

    Contact

Conditions

Explore the condition pages connected to this study.