Two-step surgery may prevent ovarian cancer without early menopause

NCT ID NCT05287451

First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 28 times

Summary

This study looks at a two-step surgery to prevent ovarian cancer in women with high-risk gene mutations (like BRCA1/2). Instead of removing both ovaries and fallopian tubes at once, the first step removes only the fallopian tubes, and the ovaries are removed later. The goal is to see if this approach is as safe and effective at preventing cancer, while possibly delaying menopause. The study involves 100 premenopausal women aged 25-50.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dana Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Email: •••••@•••••

    Contact

  • Lyndon Baines Johnson General

    RECRUITING

    Houston, Texas, 77026, United States

    Contact Email: •••••@•••••

    Contact

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Email: •••••@•••••

    Contact

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

    Contact Email: •••••@•••••

    Contact

  • Mount Sinai Health System

    RECRUITING

    New York, New York, 10029, United States

    Contact Email: •••••@•••••

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  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Email: •••••@•••••

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  • University of Washington

    RECRUITING

    Seattle, Washington, 98195, United States

    Contact Email: •••••@•••••

    Contact

  • WU St Louis

    RECRUITING

    St Louis, Missouri, 63130, United States

    Contact

    Contact

Conditions

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