Tiny study probes bone microenvironment in metastatic kidney cancer

NCT ID NCT07187869

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early study will look at how two drugs, cabozantinib and nivolumab, change the bone immune environment in 16 people with kidney cancer that has spread to bone. The main goal is to check safety and see how the bone environment responds. It is a proof-of-concept study, meaning it is too small and early to know if this approach will work.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Cabozantinib and nivolumab

What this could lead to

If successful, this could help identify better treatment options for kidney cancer that has spread to bone, potentially reducing bone complications.

What could go wrong

This is a very early, small proof-of-concept study with only 16 participants. The main goal is safety, not effectiveness, so results may not lead to new treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

nonpapillary renal cell carcinoma renal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••