New combo therapy shows promise for untreated leukemia in older adults

NCT ID NCT03586609

First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 25 times

Summary

This study tests a combination of drugs (venetoclax, cladribine, low-dose cytarabine, and azacitidine) for adults aged 50 and older with untreated acute myeloid leukemia (AML). The goal is to see if this approach can achieve complete remission. Participants receive an initial treatment phase followed by a consolidation phase. The trial is currently recruiting 145 participants at MD Anderson Cancer Center.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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