Could metal detox boost leukemia treatment? new trial aims to find out

NCT ID NCT06811233

First seen Nov 01, 2025 · Last updated Apr 24, 2026 · Updated 20 times

Summary

This study tests whether adding metal-detoxifying drugs to standard chemotherapy can improve outcomes for people with certain types of acute myeloid leukemia (AML). Researchers believe that lowering metal levels in the blood and bone marrow may help control the disease or make chemotherapy work better. About 140 adults with intermediate-risk, high-risk, or secondary AML will be randomly assigned to receive either standard therapy alone or standard therapy plus two detoxifying agents (Ca-EDTA and DMSA). The main goal is to check safety and side effects.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The University of Texas M. D. Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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