Zapping thyroid tumors without surgery: tiny trial begins

NCT ID NCT07218315

Recruiting now Disease control Sponsor: M.D. Anderson Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 3 times

Summary

This study tests a device that uses nanosecond electrical pulses to destroy small papillary thyroid cancers (up to 1.5 cm) without cutting the skin. Fifteen participants will get the outpatient procedure under local anesthesia. The main goal is to check safety and side effects, not yet to prove it works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Nanosecond pulsed field ablation (nsPFA) device
What this could lead to: If it works, this could offer a less invasive, outpatient option for treating small thyroid cancers without surgery.
What could go wrong: This is a very small early-phase trial (15 people) focused on safety, not yet proven effective. The procedure may not fully destroy the tumor or could cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

thyroid gland carcinoma thyroid gland papillary carcinoma Thyroid Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

THYROID CARCINOMA

Contacts and locations

Locations

Sarasota Memorial Hospital
RECRUITING

Sarasota, Florida, 34239, United States
The University of Texas M. D. Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States

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