New combo therapy targets aggressive brain tumors in phase 2 trial

NCT ID NCT04623931

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a more intense treatment for a fast-growing type of brain cancer called IDH wildtype glioma. It combines higher doses of radiation with the chemotherapy drug temozolomide to try to stop the tumor from growing longer. The trial will enroll 40 adults with this specific brain cancer to see if the new approach improves how long patients live without their cancer getting worse.

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Conditions

The condition(s) this trial relates to.

anaplastic oligoastrocytoma anaplastic oligodendroglioma astrocytoma (excluding glioblastoma) diffuse astrocytoma glioblastoma grade II glioma grade III glioma IDH-wildtype anaplastic astrocytoma oligoastrocytoma oligodendroglioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-••••

    Contact