WHO GRADE III GLIOMA
Clinical trials for WHO GRADE III GLIOMA explained in plain language.
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New attack on deadly brain tumors: doubling down on radiation and chemo
Disease control Recruiting nowThis study is testing whether a more intensive combination of radiation therapy and chemotherapy can better control certain aggressive brain tumors. It will involve about 40 adults with specific types of fast-growing brain cancer. Researchers aim to see if this stronger treatment…
Matched conditions: WHO GRADE III GLIOMA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 31, 2026 12:10 UTC
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New hope for kids with devastating brain tumors: trial tests flexible drug combinations
Disease control Recruiting nowThis trial is testing new drug combinations for children and young adults with aggressive brain tumors called diffuse midline gliomas (DMGs), which currently have very few treatment options. It uses a flexible 'platform' design to test different drug combinations, including ONC20…
Matched conditions: WHO GRADE III GLIOMA
Phase: PHASE2 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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New hope for kids with deadly brain tumors: trial matches treatment to tumor genetics
Disease control Recruiting nowThis study aims to find better treatments for children and young adults newly diagnosed with aggressive brain tumors. Researchers will analyze the genetic makeup of each patient's tumor to match them with a targeted therapy that might work best for their specific cancer. The goal…
Matched conditions: WHO GRADE III GLIOMA
Sponsor: Nationwide Children's Hospital • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Targeted drug trial offers hope for children with aggressive brain cancer
Disease control Recruiting nowThis study is testing a targeted drug called lorlatinib in children and young adults (ages 1-21) newly diagnosed with aggressive brain tumors (high-grade gliomas) that have specific genetic changes called ALK or ROS1 fusions. The main goals are to see if the drug can control the …
Matched conditions: WHO GRADE III GLIOMA
Phase: EARLY_PHASE1 • Sponsor: Nationwide Children's Hospital • Aim: Disease control
Last updated Mar 27, 2026 12:37 UTC
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New hope for kids with devastating brain cancer: trial tests Life-Extending drug combos
Disease control Recruiting nowThis study is testing two different drug combinations to see if they can help children and young adults with aggressive brain tumors live longer. The trial is for patients who have just finished radiation therapy. One group receives two drugs (ribociclib and everolimus), while an…
Matched conditions: WHO GRADE III GLIOMA
Phase: PHASE2 • Sponsor: Nationwide Children's Hospital • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Personal brain tumor video aims to calm fears during radiation
Symptom relief Recruiting nowThis study is testing whether a short, personalized video can reduce anxiety for brain cancer patients and their caregivers during radiation treatment. The video uses the patient's own brain scan to explain their specific tumor and potential symptoms. Researchers want to see if t…
Matched conditions: WHO GRADE III GLIOMA
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Mar 31, 2026 12:11 UTC