OLIGODENDROGLIOMA

This study is for adults with a specific, slow-growing brain tumor called a low-grade oligodendroglioma. It aims to find out if waiting to give radiation therapy until the tumor shows signs of growing again can help protect patients' memory and thinking skills, compared to starti…

This study is testing an oral drug called safusidenib for adults with specific types of brain tumors that have a genetic change called an IDH1 mutation. The main goal is to see if the drug can safely control the tumor and delay its growth or return after standard treatments. The …

This study is for adults newly diagnosed with a specific type of brain tumor called an oligodendroglioma. It aims to find out if starting with a newer combination of chemotherapy drugs (CETEG) and delaying radiation therapy is better than the current standard treatment of radiati…

This study is testing whether a more intensive combination of radiation therapy and chemotherapy can better control certain aggressive brain tumors. It will involve about 40 adults with specific types of fast-growing brain cancer. Researchers aim to see if this stronger treatment…

This is the first study in people testing an experimental pill called ONC206 for adults with recurrent brain tumors that have few treatment options. The main goal is to find the highest safe dose and understand the side effects. Researchers will enroll about 102 patients to test …

This study is testing whether combining an oral vitamin A-based drug (ATRA) with an immunotherapy (retifanlimab) can help control a specific type of recurrent brain tumor called IDH-mutant glioma. It aims to see if this combination is safe and can stimulate the patient's own immu…

This study is testing a new way to deliver cancer drugs directly to the brain for children and young adults whose brain tumors have come back or haven't responded to standard treatments. Doctors use a tiny catheter to deliver two existing drugs (cetuximab and bevacizumab) precise…

This study is testing a new psychological support program called FearLess, designed to help people with brain tumors and their caregivers manage the fear of the cancer coming back. Researchers want to see if the program is practical, acceptable, and a good fit for participants. T…

This study is testing a home-based program called HOBSCOTCH-CA, designed to help brain cancer survivors manage memory and thinking problems that often follow their illness. Participants will work one-on-one with a coach over video calls to learn problem-solving and relaxation tec…