New hope for brain tumor patients: targeted drug enters final testing phase
NCT ID NCT05303519
First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 37 times
Summary
This study tests a drug called safusidenib in people with a slow-growing brain tumor (glioma) that has a specific IDH1 gene mutation. The trial has three parts: one for recurrent tumors, one to see if the drug can prevent tumor growth after standard treatment, and one for a specific tumor type after surgery alone. About 365 adults will take part to see if the drug is safe and helps control the disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Locations
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Beijing Tiantan Hospital, Capital Medical University
RECRUITINGBeijing, Beijing Municipality, 100070, China
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44106, United States
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Columbia University Medical Center
RECRUITINGNew York, New York, 10032, United States
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
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Duke Cancer Institute
RECRUITINGDurham, North Carolina, 27710, United States
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Fred Hutch Cancer Center
RECRUITINGSeattle, Washington, 98195, United States
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Henry Ford Hospital
RECRUITINGDetroit, Michigan, 48202, United States
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Hoag Memorial Hospital Presbyterian
RECRUITINGNewport Beach, California, 92663, United States
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Huashan Hospital Affiliated to Fudan University
RECRUITINGShanghai, Shanghai Municipality, 200040, China
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Huntsman Cancer Insititute, University of Utah
RECRUITINGSalt Lake City, Utah, 84112, United States
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MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02214, United States
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Mayo Clinic - Arizona
RECRUITINGPhoenix, Arizona, 85013, United States
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Mayo Clinic - Florida
RECRUITINGJacksonville, Florida, 32224, United States
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Mayo Clinic - Rochester
RECRUITINGRochester, Minnesota, 55905, United States
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
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NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
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Orlando Health Cancer Institute
RECRUITINGOrlando, Florida, 32806, United States
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Peking Union Medical College Hospital
NOT_YET_RECRUITINGBeijing, Beijing Municipality, 100730, China
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Peter MacCallum Cancer Centre
RECRUITINGMelbourne, Victoria, Australia
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Royal Brisbane and Women's Hospital
RECRUITINGHerston, Queensland, Australia
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Royal North Shore Hospital
NOT_YET_RECRUITINGSaint Leonards, New South Wales, Australia
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Rutgers Cancer Institute
RECRUITINGNew Brunswick, New Jersey, 08901, United States
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Sanbo Brain Hospital, Capital Medical University
RECRUITINGBeijing, Beijing Municipality, 100093, China
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St Vincents Hospital Sydney (Kinghorn)
RECRUITINGDarlinghurst, New South Wales, Australia
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St. Joseph's Hospital and Medical Center
RECRUITINGPhoenix, Arizona, 85013, United States
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Stanford University
RECRUITINGPalo Alto, California, 94304, United States
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Sun Yat-sen University Cancer Center
RECRUITINGGuangzhou, Guangdong, 510060, China
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The Alfred
RECRUITINGMelbourne, Victoria, Australia
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The First Affiliated Hospital of Fujian Medical University
RECRUITINGFuzhou, Fujian, 350005, China
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UVA Health, Emily Couric Clinical Cancer Cente
RECRUITINGCharlottesville, Virginia, 22903, United States
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University of Alabama
RECRUITINGBirmingham, Alabama, 35294, United States
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University of California
RECRUITINGSan Francisco, California, 94143, United States
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University of California, Los Angeles
RECRUITINGLos Angeles, California, 90095, United States
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University of Colorado Health Cancer Care
NOT_YET_RECRUITINGAurora, Colorado, 80045, United States
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University of Florida Health
RECRUITINGGainesville, Florida, 32608, United States
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University of Kansas Medical Center
RECRUITINGKansas City, Kansas, 66160, United States
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University of Miami Health
RECRUITINGMiami, Florida, 33136, United States
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University of Texas Southwestern Medical Center
RECRUITINGDallas, Texas, 75390, United States
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University of Wisconsin Health
RECRUITINGMadison, Wisconsin, 53792, United States
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Washington University
RECRUITINGSt Louis, Missouri, 63110, United States
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West China Hospital of Sichuan University
RECRUITINGChengdu, Sichuan, 610041, China
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Xiangya Hospital of Central South University
NOT_YET_RECRUITINGChangsha, Hunan, 410008, China
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Xuanwu Hospital, Capital Medical University
RECRUITINGBeijing, Beijing Municipality, 10053, China
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Yale University
RECRUITINGNew Haven, Connecticut, 06510, United States
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Conditions
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