New drug duo takes on stubborn lung cancer

NCT ID NCT07382726

First seen Feb 03, 2026 · Last updated May 13, 2026 · Updated 14 times

Summary

This early-stage study tests a combination of two drugs, izalontamab brengitecan and adagrasib, in 18 adults with advanced KRAS G12C lung cancer that has not responded to other treatments. The main goal is to check safety and see if the combo can work better than current options for people whose cancer keeps growing despite KRAS G12C inhibitors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The University of Texas M. D. Anderson Cancer Center

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.