Zapping away thyroid nodules without surgery?

NCT ID NCT07226804

Recruiting now Disease control Sponsor: M.D. Anderson Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a new procedure called nanosecond pulsed field ablation (nsPFA) to treat benign (non-cancerous) thyroid nodules. The goal is to see if this non-surgical treatment can shrink the nodules and improve patients' quality of life. The study will enroll 30 adults who are already scheduled to receive nsPFA as part of their standard care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: nanosecond pulsed field ablation (nsPFA)
What this could lead to: If successful, this could offer a non-surgical option to shrink benign thyroid nodules and improve symptoms.
What could go wrong: This is a small, early study with only 30 participants. It is not yet known if nsPFA is better than standard care or if it has significant side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

benign thyroid gland neoplasm nodular goiter Thyroid Nodule

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PULSED-FIELD ABLATION THYROID NODULES

Contacts and locations

Locations

MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States

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