Sleep disorder

This study looks at whether the shape of a person's face influences how Botox injections change bite force in people who grind their teeth (bruxism). Participants with different facial structures receive Botox into the jaw muscle, and bite force is measured before and after treat…

This trial investigates whether structured exercise—either aerobic cycling or resistance training—can improve health-related biomarkers in women with breast cancer undergoing neoadjuvant therapy (chemotherapy or endocrine therapy before surgery). The main focus is on changes in K…

This study tested whether adding a telerehabilitation program (using a mobile app, video calls, and online coaching) to standard CPAP therapy helps obese adults with severe sleep apnea. 180 participants were followed for 6 months to see if the program improved daytime sleepiness,…

This completed study tested a remote, self-guided lifestyle program for 696 veterans with obesity and obstructive sleep apnea. Participants watched videos, completed handouts, and tracked their eating and activity, with optional coaching. The goal was to see if this low-cost appr…

This large Phase 3 trial tested a once-weekly injection called retatrutide in over 2,300 adults with obesity or overweight who do not have type 2 diabetes. The study also looked at how the drug affects knee osteoarthritis and obstructive sleep apnea. Participants received either …

This study tested the Inspire system, a device that stimulates a nerve in the neck to keep the airway open during sleep. It involved 44 adults in Singapore with moderate-to-severe obstructive sleep apnea who could not use CPAP. The main goal was to confirm the device works proper…

This study tested whether taking a melatonin supplement (3 mg each night for 6 months) could improve sleep, thinking skills, and blood sugar control in 70 adolescents with type 1 diabetes. Half received melatonin and half received a placebo. The researchers measured changes in bl…

This study tested whether a physical activity program delivered by mail and website could improve the health of nearly 50,000 older women already in the Women's Health Initiative. The program included aerobic, balance, strength, and flexibility exercises, and encouraged reducing …

This study tested whether getting a sleep doctor appointment within one month helps people with obstructive sleep apnea use their CPAP machine more regularly. About 100 adults participated. The goal was to see if faster care leads to better treatment adherence and improved sleepi…

This study compared two types of home dialysis for people with end-stage kidney disease: nighttime automated dialysis (APD) and daytime manual dialysis (CAPD). 137 non-diabetic adults tried each method for 12 weeks. The goal was to see if nighttime dialysis was as good as daytime…

This study looked at whether a diabetes drug called empagliflozin, combined with a breathing machine (CPAP), can improve sleep and heart function in 70 adults with both heart failure and obstructive sleep apnea. Participants were randomly assigned to take empagliflozin or not, an…

This study involved 155 adults with narcolepsy who were already taking a high-sodium oxybate medication. They switched to Xywav, a low-sodium version, to see if their blood pressure would improve. The goal was to provide doctors and patients with useful information about the impa…

This study tested whether a 3-year physical activity program could help prevent colon cancer from coming back in 889 patients who had surgery and chemotherapy for high-risk stage II or stage III colon cancer. Participants were randomly assigned to either the exercise program plus…

This completed phase 4 trial tested three different drug combinations to treat obstructive sleep apnea in 45 adults. The drugs aim to improve how the airway stays open during sleep. Participants took either a drug combo or a placebo before bed, and their sleep was monitored overn…

This early-stage study tested whether a brief therapy program plus a mobile app could help pregnant and postpartum women stay on their buprenorphine medication for opioid use disorder. Fifteen pregnant women took part, attending therapy sessions and using the app for up to 9 mont…

This completed trial tested whether a low-level laser device (Alesis OSA-1) can reduce breathing pauses in adults with obstructive sleep apnea. 35 participants received six 12-minute light treatments over three weeks. Researchers measured apnea events before and after treatment, …

This study tested whether adding the sleep medication lemborexant (Dayvigo) to the standard alcohol craving drug naltrexone helps people with alcohol use disorder and insomnia. Eight adults took either the combination or naltrexone plus a placebo. Researchers measured alcohol cra…

This study looked at whether weight-loss surgery (sleeve gastrectomy) is better than diet and medication for adults aged 65 and older with severe obesity and related health problems like type 2 diabetes, high blood pressure, sleep apnea, and knee arthritis. Sixty patients chose e…

This completed study tested whether painting metal roofs with a special heat-reflecting coating can lower indoor temperatures and improve health in Niue, a Pacific island nation facing record heat. Researchers enrolled 288 adults living in single-story homes with metal roofs. The…

This study tested if transplanting healthy gut bacteria (fecal microbiota) can help people with chronic insomnia. 80 adults received either the bacteria or a placebo in capsules. Researchers measured sleep quality using sleep tests and questionnaires to see if the treatment impro…

This study looked at 61 night workers aged 20-55 to understand how their sleep patterns relate to attention and heart rate. Participants took ramelteon (Rozerem), a drug similar to melatonin, for two weeks. Researchers measured changes in sleep quality, anxiety, and depression us…

This study tested whether managing sleep apnea remotely with a breathing device (APAP) can lower blood pressure as well as traditional in-person care. Researchers enrolled 344 adults with suspected sleep apnea in Beijing. Participants were randomly assigned to either telemedicine…

This study looked at whether using a CPAP machine at night can reduce episodes of atrial fibrillation (a type of irregular heartbeat) in people who also have obstructive sleep apnea. Twenty-five adults with both conditions were enrolled. Half used CPAP while the other half were o…

This phase 2 trial tested a drug called lorundrostat in 48 adults with moderate-to-severe obstructive sleep apnea and high blood pressure. Participants took either the drug or a placebo for four weeks to see if it improved breathing during sleep and lowered blood pressure. The st…

This study looked at 19 people with sleep apnea and mild high blood pressure. It compared a drug called bosentan to the standard CPAP machine to see if the drug could lower blood pressure just as well. The goal was to find a simpler way to manage heart risks in sleep apnea patien…

This completed trial tested a device called AesyBite Active, which uses gentle vibrations to reduce teeth grinding (sleep bruxism) during the night. 26 adults who grind their teeth wore the device while sleeping. The main goal was to see if it could cut grinding activity by at le…

This study tested a new, low-cost device called Apne-Scan to see if it can accurately detect sleep apnoea compared to standard home tests. Forty adults referred to a sleep clinic wore the Apne-Scan mask alongside their usual test overnight. The goal was to see if the simpler, che…

This study looked at whether monitoring oxygen levels at home for 14 nights gives a more accurate diagnosis of obstructive sleep apnea than the standard single-night test in a hospital. Researchers enrolled 130 adults with suspected sleep apnea. They compared results from home mo…

This study tested a wearable device called SUNRISE to see if it can accurately screen for obstructive sleep apnea in people with diabetes or chronic lung disease. Researchers compared its results to standard sleep testing in 37 adults. The goal is to make sleep apnea screening ea…

This study tested a wearable ring device (Belun Ring) to see if it can accurately screen for obstructive sleep apnea. 70 adults wore the ring during a standard overnight sleep test. The ring measures oxygen levels, pulse, and movement to estimate breathing disruptions. Researcher…

This study looked at whether a portable sleep monitor used during a short hospital stay can accurately diagnose sleep apnea in people with multiple system atrophy (MSA), compared to the standard overnight lab test. Thirty adults with probable MSA took part. The goal was to see if…

This study tested whether a Samsung Galaxy Watch can reliably detect moderate to severe obstructive sleep apnea (OSA) in adults. Researchers enrolled 152 people who were at high risk or already diagnosed with OSA. The watch's readings were compared to standard sleep tests to see …

This study tested whether a ring-shaped device worn on the finger can accurately diagnose obstructive sleep apnea compared to the standard overnight sleep lab test. 136 adults suspected of having sleep apnea wore the Belun Ring while also undergoing standard lab testing. The goal…

This study tested whether a special algorithm in a pacemaker can accurately diagnose sleep apnea in people with heart problems. Researchers compared the pacemaker's readings to a standard overnight sleep test in 66 participants. They also looked for a link between sleep apnea sev…

This study tested a headband called Dreem 3S that people wear at home to monitor sleep and wake patterns. The goal was to see if it can help diagnose narcolepsy, a condition that causes extreme daytime sleepiness. 78 adults took part, and researchers checked how well the device w…

This completed study tested a new radioactive tracer called [18F] - FD17 for PET imaging to detect clumps of a protein called alpha-synuclein in the brain. These clumps are linked to Parkinson's disease, multiple system atrophy, and a sleep disorder that often precedes Parkinson'…

This study tested whether giving extra health coaching to new parents—especially fathers—could help prevent rapid weight gain in babies and reduce obesity risk. Researchers enrolled 657 parents from Massachusetts General Hospital and randomly assigned them to either receive coach…

This study tested whether telehealth coaching from a nurse, based on cognitive behavioral therapy for insomnia (pCBT-I), could prevent or reduce insomnia and depression in 167 adults with low income or education. Participants had early signs of insomnia and were coached to improv…

This completed study tested a program to prevent obesity in mothers and children from pregnancy to age 2. It involved 1,645 families at community health centers in Boston. The program used education, text messages, and provider training to promote healthy eating, physical activit…

This study tested a behavioral sleep program for 16 depressed teenagers who slept less than 7 hours on school nights or had irregular sleep schedules. The program included one session with a provider and used smartphone tools to help teens create a plan for longer and more regula…

This study tested whether taking hydrocortisone (a cortisol-like hormone), melatonin, or both could reduce jet lag symptoms after long eastward flights. Fifty-seven healthy adults aged 18-65 who flew across 6-8 time zones took the pills for 4 days after arrival and reported their…

This study tested a combination of two drugs, atomoxetine and oxybutynin (called AtoOxy), as a potential pill-based treatment for obstructive sleep apnea (OSA). 117 adults with OSA who were not using CPAP took the medication for one month. The goal was to see if the drug combo co…

This study tested whether bright light therapy could help people with multiple sclerosis who have trouble sleeping. 27 participants used a light box at home. The goal was to see if it was safe and if it improved sleep and daily function.

This completed pilot study tested whether shining a low-level laser into the blood (intravenous laser therapy) can improve sleep and reduce pain in people with chronic sciatica. Sixty-six adults with sciatica and poor sleep received either electroacupuncture alone or electroacupu…

This study tested whether a plant-based melatonin supplement (phytomelatonin) from tomatoes can improve sleep quality better than synthetic melatonin or a placebo. 244 adults with poor sleep took one capsule nightly for 28 days. Sleep was tracked with a wearable ring and question…

This study tests an oral drug called SDX (serdexmethylphenidate) to see if it safely reduces excessive daytime sleepiness in adults with idiopathic hypersomnia, a condition where people feel extremely sleepy during the day despite getting enough sleep at night. Participants will …

This study tests two behavioral therapies—imagery rehearsal therapy (IRT) and targeted dream control (TDC)—to reduce nightmares in adults with narcolepsy. Participants attend therapy sessions, keep a daily sleep log, and complete questionnaires. Some Chicago-area participants als…

This study looked at whether extra family support helps children with Down syndrome and obstructive sleep apnea use their positive airway pressure (PAP) machine more regularly. 27 children aged 6-18 were split into two groups: one received standard care, the other got a family-in…

This phase 3 study tests whether YZJ-1139 tablets help adults with insomnia fall asleep faster and sleep more efficiently. Participants receive either 20 mg, 40 mg, or a placebo daily for two weeks. Sleep is measured using both sleep diaries and overnight lab tests.

This trial investigates whether jaw exercises (Rocabado programme) work better when guided by a physiotherapist through online video sessions versus doing them at home with written instructions alone. Adults aged 18-60 with jaw-joint pain and teeth grinding are randomly assigned …

This clinical trial tests whether a new drug called YZJ-1139 can help people with insomnia sleep better than the commonly used medication zolpidem. Adults aged 18 to 64 with insomnia disorder take either YZJ-1139 or zolpidem daily for 28 days. Researchers measure sleep quality us…

This study tested whether Benson relaxation exercises can improve sleep quality in cancer patients. 72 adults with cancer were randomly assigned to do relaxation exercises or receive a sleep hygiene booklet. The goal was to see if this simple, non-drug method could help with slee…

This study tests whether a one-month program of isometric neck exercises and posture advice can reduce cervicogenic headaches, stress, and sleep problems in 44 adolescents aged 13-19 who use smartphones at least 4 hours daily. Participants will be randomly assigned to either the …

This study tested whether adding telehealth coaching to a digital cognitive behavioral therapy program helps people with insomnia complete the treatment. 700 adults with insomnia were enrolled. The goal was to see if coaching improves adherence and reduces disparities in who bene…

This study tested two simple treatments for snoring in people with mild sleep apnea: low-level laser therapy applied to the mouth and soft palate, and oropharyngeal exercises (like tongue and throat workouts). 180 adults aged 40-55 took part. The goal was to see which approach re…

This completed study tested two ways to improve sleep in children aged 1 to 7 years: a mobile app (Storybook) that guides caregivers through calming bedtime activities, and face-to-face sessions teaching sleep hygiene and routines. Sixty families in Ecuador took part over one mon…

This study tested whether daily gummies containing L-theanine and lion's mane mushroom extract could reduce stress, anxiety, and improve sleep in university students. 67 students aged 18-25 took either the gummies or no supplement for 8 weeks. The goal was to see if this natural …

This study tested whether a mild electrical current applied to the head (called transcranial electrostimulation, or TES) can help control pain after major sleep apnea surgery. 45 patients received TES along with standard care. The goal was to see if TES reduces pain and the need …

This study tests if group cognitive behavioral therapy (CBT) can reduce anxiety and insomnia in teens aged 12-20. About 171 participants with both conditions will receive either CBT for anxiety or CBT for insomnia. The goal is to see which approach better improves symptoms, sleep…

This study tested whether a daily 150mg sustained-release ashwagandha supplement can reduce disturbed sleep in 54 adults with poor sleep quality. Participants took either the supplement or a placebo for 28 days and wore an Oura ring to track how often they woke up after falling a…

This study tested whether a noninvasive device that gently stimulates a nerve in the ear (taVNS) could help breast cancer patients with insomnia. Twenty adults with stage I-IV breast cancer who had trouble sleeping for at least three months took part. The main goal was to see if …

This study tests two short behavioral therapies delivered over video calls for adults with chronic orofacial (jaw or face) muscle pain and insomnia. One therapy focuses on sleep habits and routines; the other uses jaw relaxation and breathing exercises. The goal is to see which a…

This study tests whether cognitive behavioural therapy for insomnia (CBT-I) can improve sleep and ADHD symptoms in adolescents aged 12 to 18 who have both ADHD and insomnia. Participants receive either CBT-I plus usual care or usual care alone. The goal is to see if addressing in…

This study tested whether teaching good sleep habits could help people with painful diabetic nerve damage sleep better and feel better overall. Twenty-four patients were split into two groups: one received a booklet and face-to-face sleep training from a nurse, while the other co…

This study tested a combination of platelet-rich plasma (PRP) from the patient's own blood and hyaluronic acid injected into the jaw joint. Twenty-two adults with painful clicking and limited mouth opening received the treatment. Researchers used a jaw tracking device to measure …

This Phase 2 trial tested AXS-12 (reboxetine) in 21 adults with narcolepsy and cataplexy. Participants received either the drug or a placebo for three weeks, then switched. The goal was to see if AXS-12 could reduce weekly cataplexy attacks and improve excessive daytime sleepines…

This study tested a 12-week remotely-supervised rehabilitation program for 60 men aged 25-65 with moderate to severe obstructive sleep apnea. The goal was to see if the program could improve breathing pauses during sleep, daytime sleepiness, and overall quality of life. Participa…

This study tested whether an AI-guided writing program could help teens feel less anxious, depressed, or stressed. Over three days, 486 Chinese adolescents wrote about negative experiences, with some receiving personalized AI feedback. The goal was to see if this simple, digital …

This study tested a new medicine called ALKS 2680 in 92 adults with narcolepsy type 1, a condition that causes severe daytime sleepiness and sudden muscle weakness (cataplexy). Participants stopped their usual narcolepsy medications and received either ALKS 2680 or a placebo for …

This study tested a technique called cryo-auriculotherapy, where a device freezes specific spots on the ear, to see if it helps people with chronic insomnia. Sixty-five adults with moderate to severe insomnia received either real or sham (fake) treatments over three months. The m…

This study tested whether reducing non-urgent nighttime medical interruptions helps hospitalized adults sleep better. 51 patients wore Fitbits to track sleep and completed sleep quality surveys. One group had adjusted nighttime orders with fewer interruptions, while the other rec…

This trial tests whether applying platelet-rich fibrin (PRF) — a wound dressing made from a patient's own blood — to the roof of the mouth after gum graft surgery improves pain, sleep, and overall quality of life compared to standard dressings. About 78 adults needing gum surgery…

This study tested whether a herbal supplement called Redormin 500 (made from valerian and hop extracts) can help people with occasional sleep problems think more clearly during the day and feel better overall. Forty healthy adults with mild sleep issues took either the supplement…

This study looked at whether watching a video through virtual reality goggles with music can reduce pain and improve sleep quality in women with period pain (dysmenorrhea). 77 women aged 15-49 with moderate to severe pain used either VR with music or just music alone for 3 days. …

This study tested a text-message chatbot called Cecebot that combines sleep therapy and activity tips to help breast cancer survivors with insomnia. 60 women with stage I-III breast cancer and poor sleep used the chatbot for 6 weeks. The goal was to see if it was easy to stick wi…

This study tested whether eye masks and calming audiobooks could improve sleep for children aged 6-15 in the pediatric intensive care unit. Forty-two children were randomly assigned to use these tools or receive standard care. Researchers measured sleep quality and vital signs to…

This study tested a six-session behavioral sleep program, called Apnea and Insomnia Relief (AIR), in 118 Gulf War veterans with Gulf War Illness. The program combined sleep education, motivation for using a breathing machine, and insomnia therapy, all done via telehealth. Researc…

This study tests whether repeated acupressure can help reduce agitation, pain, and sleep disturbances in intensive care unit (ICU) patients who are on mechanical ventilators. Participants receive either real acupressure or a light touch (sham) twice daily for four days. Researche…

This study looked at whether a swaddle blanket with a gentle abdominal band can reduce acid reflux, breathing pauses, heart rate drops, and low oxygen levels in premature infants. About 50 babies in the NICU were observed to see if the blanket helped. The goal was to find a simpl…

This study tested whether a drug called acetazolamide can improve sleep-disordered breathing in women traveling to high altitude (3600 m). 303 healthy adults participated in a randomized, placebo-controlled trial. The main goal was to see if the drug reduced drops in oxygen level…

This study looked at whether taking gac fruit oil capsules for 30 days could help adults aged 40 to 65 who have trouble sleeping. The 50 participants took four capsules daily and were tested on sleep quality, vision, mood, and brain scans before and after. The goal was to see if …

This study looked at whether surgery to fix a blocked nose can improve snoring and sleep apnea in adults. Thirty people with nasal obstruction and sleep apnea had surgery. The main goal was to see if their breathing pauses during sleep (measured by the apnea-hypopnea index) got b…

This study tested different treatments to help with sleep problems caused by Long COVID. It involved 361 adults and looked at improving daytime sleepiness and overall sleep quality. The goal was to find which treatments work best for these specific sleep issues.

This study tested whether wearing special light glasses for 30 minutes each morning could help breast cancer patients feel less tired, sleep better, and think more clearly during treatment. The trial included 260 women with early-stage breast cancer, plus a healthy comparison gro…

This study looked at whether a 4-week behavioral sleep program could improve both sleep and thinking in 62 older adults with chronic insomnia. Participants learned sleep habits, relaxation, and adjusted their bedtimes. The researchers measured sleep changes and daily thinking per…

This study tested two sleep medications, trazodone and eszopiclone, in 673 veterans with PTSD-related insomnia. The goal was to see if these drugs could reduce insomnia symptoms over 12 weeks. Participants were adults aged 18-75 with military-related PTSD and insomnia. The study …

This study looked at whether different lengths of light exposure can improve sleep, mood, and agitation in people with Alzheimer's disease. 135 participants were randomly assigned to receive 2 hours, 4 hours, or all-day morning light. The goal was to see which light schedule work…

This completed trial tested whether combining online acceptance and commitment therapy (ACT) with customized sound therapy helps people with tinnitus and insomnia. 164 adults were split into two groups: one received both therapies, the other only sound therapy. The goal was to se…

This study tested two simple treatments—melatonin pills and tailored light therapy—to help people with Long COVID who have trouble sleeping. About 470 participants were randomly assigned to receive either melatonin, a placebo, or light therapy. The goal was to see if these treatm…

This study tested whether a 14-day course of the sleep medication eszopiclone could help people with both insomnia and obstructive sleep apnea use their CPAP machine more consistently. Sixty participants were randomly assigned to receive either eszopiclone or a placebo. The resea…

This study tested whether a Persian-language internet program called Omid, based on cognitive behavioral therapy, can improve sleep in adults with insomnia. Thirty participants were randomly assigned to use the program or receive usual care. The program includes weekly online les…

This study tested a six-session behavioral therapy that teaches people with narcolepsy type 1 how to become aware during dreams (lucid dreaming) and control frightening images. Ninety-eight adults took part, with half receiving the therapy and half getting standard care. The goal…

This study tested an experimental drug called AXS-12 (reboxetine) in 90 people with narcolepsy who experience cataplexy (sudden muscle weakness) and excessive daytime sleepiness. Participants took either the drug or a placebo twice daily for several weeks. The main goal was to se…

This study tested a new daily supplement called KGA-10 (a heat-killed bacterium) in 107 healthy adults to see if it could lower stress, reduce inflammation, and improve sleep and general well-being. Participants took either the supplement or a placebo for 8 weeks and completed su…

This study followed 90 Canadian adults with insomnia who were prescribed daridorexant. Researchers tracked changes in quality of life, work productivity, and sleep symptoms over three months using questionnaires. The goal was to see how the medication helps people in everyday lif…

This study tested whether using a CPAP machine (a device that helps you breathe during sleep) can also improve oral frailty (weakness in the mouth) and dysphagia (trouble swallowing) in people with obstructive sleep apnea. Researchers followed 450 adults aged 50 and older for six…

This completed trial tested whether a combination of physical activity (the Otago program) and cognitive training (using the CogniFit app) could improve sleep and quality of life in people over 65. Sixty-six participants were split into groups: one did the physical program, anoth…

This study tested three behavioral approaches—sleep restriction, stimulus control, and systematic light exposure—to help gynecologic cancer survivors who have trouble sleeping. 78 participants completed the program, and researchers measured changes in sleep quality and daytime im…

This small study tested a dietary supplement called NatureU Sweet Dream, which contains GABA and Lactium, against a standard melatonin product in 17 adults with mild to moderate sleep problems. Participants wore a sleep tracker to measure deep sleep duration and percentage. No si…

This study tested three treatments for chronic teeth grinding (bruxism): dry needling and two types of botulinum toxin (Botox). 72 adults with severe jaw pain were split into three groups. Researchers measured pain levels and jaw muscle thickness before treatment and up to 3 mont…

This study tested whether laughter yoga and sleep hygiene training could help university students with premenstrual syndrome (PMS). 45 female students took part in 4 weekly 45-minute laughter yoga sessions plus sleep hygiene advice. Researchers measured changes in PMS symptoms, s…

This study looked at whether an 8-week group exercise program could improve physical abilities and sleep in adults aged 65 to 90. Eighty participants from community centers in Taiwan either joined the exercise program or continued their usual activities. The program included aero…

This study tested a home-based brain-training program in 12 autistic adults who also had insomnia. Participants played cognitive games for 18 hours over 6 weeks while wearing a sleep tracker and filling out sleep diaries. The goal was to see if the training was usable and could i…

This study tested two types of therapy for insomnia in 134 people also being treated for alcohol use disorder. The goal was to see if improving sleep could help them stay sober and feel better during the day. Participants received either a standard insomnia treatment or a tailore…

This study tested three ways to treat jaw pain caused by teeth grinding (bruxism): a custom mouthguard (occlusal splint), Botox injections, or both together. Sixty adults completed the 3-month trial. Researchers measured pain and jaw function changes to see which approach worked …

This study tested whether sleeping with the head and trunk raised (using an adjustable bed backrest) improves sleep quality in people with chronic obstructive pulmonary disease (COPD). Twenty-four adults with severe COPD and sleep difficulties each tried the raised position and t…

This study tested whether a medication called solriamfetol, cognitive behavioral therapy for insomnia (CBT-I), or both together can help people with insomnia sleep better and feel less tired during the day. 115 adults with insomnia took part. The goal was to see if staying awake …

This study tested whether a simple internet-based self-help program could help people with long-term insomnia stop using sleeping pills like benzodiazepines or Z-drugs. The program used sleep restriction and stimulus control techniques. 62 adults who had been taking sleep medicat…

This study tested whether a mindfulness program could help teenagers with obstructive sleep apnea use their CPAP machine more regularly. 37 teens aged 13-18 with moderate to severe sleep apnea took part. The program taught skills like awareness and resilience, and the researchers…

This study tested whether a short course of the steroid dexamethasone can reduce the severity of obstructive sleep apnea in children aged 2 to 10. Ten children with moderate-to-severe sleep apnea received either the drug or a placebo for three days. The goal was to see if the ste…

This study tested a once-nightly extended-release form of sodium oxybate (FT218) in 157 adults with idiopathic hypersomnia, a condition causing excessive daytime sleepiness despite adequate sleep. Participants were already on stable doses of stimulants or other alerting agents. T…

This study looked at whether a deep dental cleaning (called subgingival instrumentation) can reduce jaw symptoms like pain, stiffness, and tension in people who grind their teeth (bruxers) and also have gum disease (periodontitis). Sixty adults aged 30-40 received the cleaning, a…

This study tested a dietary supplement called Speed Sleep in 60 adults aged 18-65 who have trouble sleeping. Participants took either the supplement or a placebo daily for 4 weeks. Sleep quality and quantity were measured using Fitbit trackers and questionnaires.

This study tested whether a guided meditation called yoga nidra is practical and helpful for people with PTSD and insomnia. Sixty adults who had experienced a stressful or traumatic event and had trouble sleeping took part. They listened to online recordings daily for 8 weeks, an…

This study tested an early sleep facilitation program for preterm infants and their caregivers. The program includes sleep training in the hospital and guidance for caregivers after discharge. Researchers measured infant sleep, health, and caregiver stress, sleep, quality of life…

This study tested whether sleeping in a semi-upright position (45-degree angle) after surgery could prevent sleep apnea from getting worse. 164 adults with sleep apnea who were having elective inpatient surgery took part. Half slept semi-upright and half slept flat on their backs…

This study looked at whether wearing compression stockings during the day for 28 days could reduce the number of breathing pauses (apneas) per hour in people with moderate to severe sleep apnea. The idea is that stockings prevent fluid from building up in the legs and moving to t…

This early-stage study tested a new insomnia drug called HEC83518 in 74 healthy Chinese adults aged 18 to 45. The main goal was to check safety and side effects after a single dose. Researchers also measured how the drug moves through the body. This is a first step to see if the …

This early-stage trial tested a new drug called HEC83518 in 57 healthy Chinese adults to see if it is safe and how the body processes it. Participants took the drug or a placebo daily for 15 days. The study focused on side effects and drug levels in the blood, not on whether it i…

This study tested whether a self-help book could help healthcare workers with shift work disorder sleep better and feel less sleepy. 199 participants with symptoms of the disorder took part. The book provided tips on managing sleep, alertness, and health related to shift work.

This study tested a 3-month walking program for Spanish-speaking Latinos aged 55 and older with mild cognitive impairment. Participants walked in groups twice a week, then received motivational phone calls for another 3 months. Researchers measured changes in physical activity, t…

This small study tested whether combining digital cognitive behavioral therapy for insomnia (CBT-I) with sessions in a sauna blanket is feasible for adults with insomnia. Ten participants used an online CBT-I program and a sauna blanket at home for 9 weeks. The goal was to see if…

This completed trial tested PeptiSleep, a plant-based supplement made from rice protein, to see if it improves sleep quality in healthy adults. 120 participants took either PeptiSleep or a placebo daily for 6 weeks while wearing a sleep tracker and completing surveys. The study m…

This study tested a cognitive behavioral therapy (CBT) course for insomnia in 73 adults who also have a chronic physical illness like arthritis, heart disease, or cancer. The therapy focused on changing sleep habits and thoughts about sleep. Results showed that the course helped …

This study tested whether a desk lamp that gives off near-infrared light can help people who feel sleepy or down during the day. Eighty healthy adults aged 25 to 65 used the lamp at their desk for two weeks. Researchers checked changes in mood, drowsiness, sleep quality, and bloo…

This study looked at whether taking a whey protein supplement twice a day helps adolescent soccer players improve their performance, recover faster, and change body composition during a 10-12 week competitive season. Thirty-one high school players aged 13-18 took either the prote…

This study tested a 10-week digital detox program for 160 teens aged 10-19 who use smartphones at least 3 hours daily. The program included weekly sessions on reducing screen use, setting goals, and improving sleep habits. Researchers measured changes in screen addiction, sleep q…

This pilot study tested whether wearing bright light therapy glasses can improve sleep and reduce cravings in people being treated for opioid use disorder. Twenty-three adults on stable medication-assisted treatment (methadone or buprenorphine) with insomnia used either active or…

This study tested whether walking while doing simple mental tasks (like memory or attention exercises) can help older adults with brain fog. 90 people aged 65+ took part, either walking with cognitive tasks or walking only, three times a week for four weeks. Researchers measured …

This study looked at whether exercising in the morning or evening helps control blood sugar better in pregnant women with gestational diabetes or glucose intolerance. 39 women walked or stepped for 30 minutes either after breakfast or after dinner. The researchers measured blood …

This study tested a phone-based health coaching program to help people with sleep apnea use their positive airway pressure (PAP) device more often. 27 adults who were not using their device enough took part. The coaching aimed to improve device use and reduce daytime sleepiness.

This study looked at whether breathing exercises plus lavender essential oil can reduce job burnout and improve sleep in nurses who work rotating shifts. 70 nurses took part. The goal was to see if this simple, drug-free approach could help them feel less exhausted and sleep bett…

This completed study tested whether progressive relaxation exercises could help patients sleep better after urological surgery. Two adults aged 18 or older, with no sleep disorders, practiced tensing and relaxing muscles while focusing on breathing. The goal was to see if this si…

This study tested whether wearing a smart watch and using a health app could help people with obstructive sleep apnea use their CPAP machine more regularly. 46 adults who either had never used CPAP or used it less than 4 hours a night were given a smart watch and app for 90 days.…

This study tested whether laughter yoga could help women in menopause who struggle with brain fog, low mood, and poor sleep. 97 women were split into two groups: one did 8 sessions of laughter yoga over 4 weeks, and the other did nothing. Researchers measured brain fog, psycholog…

This study tested two pelvic floor muscle strengthening methods—EMG-biofeedback and rebound therapy (gentle bouncing)—in 42 women with endometriosis. The goal was to see which better reduces pain, improves muscle strength, and boosts quality of life. Participants had moderate to …

This study tested the DOZE app, a digital self-management program designed to improve sleep in young adults aged 18-25 with chronic pain and insomnia. Forty participants used the app and a sleep diary for 10 weeks. The goal was to see if the app is easy to use and helps with pain…

This small study looked at 17 adults with bruxism (teeth grinding) who received Botox injections into their jaw muscle. Researchers used ultrasound to measure muscle thickness and texture before treatment, at 14 days, and at 90 days. They also tracked pain levels. The goal was to…

This study tested whether taking melatonin before bed can reduce pain and improve sleep in people with chronic low back pain and insomnia. About 220 adults aged 18 to 64 with back pain for at least 3 months and sleep problems took either melatonin or a placebo for several weeks. …

This study looked at whether Reiki, a hands-on relaxation technique, can reduce pain, fatigue, and improve sleep in older adults living in nursing homes. Sixty people aged 50 and older with chronic pain took part. They received Reiki sessions over four weeks, and researchers meas…

This completed study tested whether semaglutide, a drug used for type 2 diabetes and weight loss, could improve sleep apnea in 15 people with diabetes or obesity. Researchers measured breathing pauses during sleep (AHI) after 1 and 4 weeks of treatment. The goal was to see if the…

This study tested whether partial-body cryotherapy (standing in a very cold chamber for 2-3 minutes) could help reduce fatigue in people with multiple sclerosis during a rehabilitation stay. 43 participants received either real cryotherapy at -120°C or a sham version at -30°C ove…

This study tested whether an online program for insomnia could help veterans with COPD sleep better and feel better. 13 veterans were randomly assigned to either the online insomnia treatment or online education about sleep. The goal was to see if the treatment improved sleep qua…

This study tested whether a type of talk therapy called Acceptance and Commitment Therapy (ACT) can improve sleep in adults with insomnia. 93 participants were randomly assigned to either receive ACT for 7 weeks or join a waitlist. The therapy encourages people to stop struggling…

This study looked at whether kinesio taping (a special elastic tape placed on the skin) can quickly ease period pain and related symptoms like trouble sleeping and fear of moving. Researchers compared real taping to a fake (sham) taping in 24 women aged 18-24 with primary dysmeno…

This study looked at whether eating microgreens can improve sleep patterns in athletes. Twenty active athletes without heart disease took part. Researchers measured sleep stages, total sleep time, and muscle soreness to see if microgreens help with recovery and rest.

This study tested whether pillows filled with herbs can improve sleep and quality of life. Thirty healthy adults used the pillows for two weeks while wearing a sleep monitor and filling out questionnaires. The goal was to see if a simple, natural approach could help people sleep …

This study looked at whether a short sleep therapy program (BBTI) can improve sleep and help people stay in treatment for substance use disorders. About 83 adults living in a residential recovery program took part. They wore sleep trackers, completed surveys, and did sleep diarie…

This study tested whether the sleep medication suvorexant (Belsomra) can reduce insomnia severity and improve metabolic health in midlife women who have both insomnia and signs of metabolic syndrome. Thirty-one healthy women aged 40-65 who were perimenopausal or postmenopausal to…

This study tested a program called SIESTA-Rehab to help stroke patients sleep better during their hospital stay. The program included training nurses to reduce nighttime disruptions and a plan to check for and treat sleep apnea. Researchers studied 400 adults in a rehab hospital …

This study tested whether a dental mouthpiece (mandibular advancement device) can reduce frequent nighttime urination in adults with obstructive sleep apnea. Eleven participants who woke up to pee at least twice a night used the device and tracked their bathroom visits. The goal …

This study looked at whether a 12-week exercise program could help older adults become less frail, improve their memory and thinking, and get better sleep. 110 adults aged 65 and older took part. The program included group exercise sessions twice a week. Researchers measured frai…

This study looked at whether smelling lavender can help people over 65 sleep better and have better physical balance. 90 older adults took part, and researchers measured sleep quality and balance before and after using lavender scent. The goal was to find a safe, non-drug way to …

This study looked at whether therapeutic touch—a gentle, non-invasive technique—can help people aged 65 to 85 who are in the hospital sleep better and feel less anxious. Researchers compared a group that received therapeutic touch to a control group. The goal was to see if this s…

This study looked at whether aromatherapy (lavender oil foot massage) and reflexology (pressing specific points on the feet) could reduce pain and improve sleep in 90 children with cerebral palsy, aged 6 to 12. Children were split into three groups: aromatherapy, reflexology, or …

This study tested whether a gentle, light-touch therapy (therapeutic touch) could help advanced cancer patients in palliative care sleep better and feel less tired. Sixty-one patients were randomly assigned to receive either 5 days of 10-15 minute touch sessions or standard care.…

This study tested whether teaching menopausal women about good sleep habits (sleep hygiene) could improve their sleep and comfort. Sixty women were split into two groups: one received the education, the other did not. Researchers measured sleep quality and comfort before and afte…

This study looked at two treatments for jaw pain caused by teeth grinding (bruxism) and related muscle pain. Forty adults either got a custom mouth splint to wear most of the day or had thin needles inserted into their jaw muscles (dry needling) in three weekly sessions. Research…

This study tested whether combining virtual reality (VR) with aromatherapy could improve the mental well-being of older adults living in care homes. 48 participants used VR and scents to see if it boosted happiness, reduced stress, improved sleep, and increased life satisfaction.…

This study tested a sleep improvement program for people with cancer and their intimate partners who also have sleep problems. The goal was to reduce insomnia and improve sleep quality. Only 2 couples took part, so results are very limited.

This study tested an online program to help cancer patients with insomnia. It included 348 adults with cancer who had trouble sleeping. The program used cognitive-behavioral techniques and aimed to see who might need extra help from a professional.

This study tested a version of cognitive behavioral therapy for insomnia, specially adapted for night shift workers. 60 nurses who work night shifts and have insomnia took part. The goal was to see if the therapy is practical and helps improve sleep and reduce fatigue.

This study tested whether Eschscholzia tablets, a herbal product, can help adults with insomnia sleep better. 104 people took either the tablets or a placebo for 4 weeks, and neither they nor the researchers knew who got which. The goal was to see if the tablets improve sleep qua…

This study tested a mobile app called PCYCARE in 120 first-time pregnant women in their third trimester. The app provides educational modules and guided relaxation sessions over 21 days. Researchers measured changes in anxiety, sleep quality, and childbirth preparedness compared …

This study tested two programs to help older adults stop taking sleeping pills like lorazepam or zolpidem. One program focused on placebo effects—the power of believing a treatment works—while the other did not. Both included cognitive behavioral therapy and special pill packagin…

This small study tested whether wearing bright light glasses each morning could improve symptoms of irritable bowel syndrome (IBS) and reduce leaky gut. Five adults with IBS used the light device for two weeks. The goal was to see if the light therapy eases belly pain, bloating, …

This study looked at whether progressive relaxation exercises can help people with type 2 diabetes who have nerve pain, fatigue, and poor sleep. 88 adults took part. The goal was to see if these simple exercises could improve their symptoms and quality of life.

This study tested a device called BTL-699-2 in 43 adults to see if it could improve sleep quality and reduce stress. Participants received six treatments and filled out questionnaires about their sleep and stress levels. The goal was to find a non-drug way to help people sleep be…

This study looked at whether teaching primary care doctors better ways to treat insomnia can help their patients sleep better. About 485 patients with insomnia symptoms completed surveys. Researchers compared patients whose doctors received special training with those getting usu…

This study tested whether teaching women in menopause about good sleep habits (sleep hygiene) could improve their sleep quality and reduce common menopause symptoms like hot flashes and mood changes. Seventy women who had not had a period for at least a year took part. They recei…

This study tested an online program called SLEEPexpert that teaches behavioral techniques to improve sleep in people with mental disorders. 68 psychiatric inpatients with insomnia used the program alongside their usual treatment. The goal was to see if it helps reduce insomnia an…

This study tested whether a six-week sleep therapy program (CBT-I) could improve thinking and memory in older adults aged 60-85 with insomnia. Two hundred participants were randomly assigned to either CBT-I or a sleep education program. A small group also had brain scans to see i…

This study tested a sleep improvement program designed for both people with Alzheimer's disease and the family members who care for them. The program was tailored to address sleep problems in both the patient and caregiver at the same time. The goal was to see if this approach co…

This study tested a dietary supplement called NP-2006 in 48 healthy adults who had mild, ongoing sleep troubles (subclinical insomnia). Participants took either the supplement or a placebo pill daily before bed for 4 weeks. Researchers measured sleep quality and daytime sleepines…

This study tested whether wearing an eye-ear sleep band, which blocks light and noise, could improve sleep quality in 100 adults admitted to a coronary care unit with acute coronary syndrome. Each patient spent one night with the band and one night with standard care, in random o…

This small study tested a robotic device that massages the back to see if it helps people with Parkinson's disease move better, feel less back pain, and sleep better. Nineteen adults with mild to moderate Parkinson's took part in four 40-minute sessions over two weeks. The result…

This study looked at whether drinking tart cherry juice can improve sleep in older adults with insomnia. Twenty people aged 65 and older drank cherry juice and a placebo for 4 weeks each while wearing a sleep tracker. Researchers checked if the study was easy to follow and measur…

This study looked at whether sucking on ice (oral cryotherapy) can reduce sore throat and improve daily life in people with sleep apnea after robotic surgery. 64 adults took part. The goal was to see if this simple, low-cost method could ease pain and help patients get back to no…

This study tested a sleep medication called lemborexant in 82 adults with liver cirrhosis who had trouble sleeping. The drug works by blocking wakefulness signals in the brain. Researchers measured sleep quality and checked for side effects on the liver. The goal was to see if le…

This study tested whether acupressure—a technique using finger pressure on specific body points—can improve pain, anxiety, sleep quality, and the sense of nursing presence in intensive care patients. Sixty adults in the ICU were split into three groups: one received real acupress…

This study tested whether Liuzijue Qigong, a traditional Chinese breathing exercise, could improve lung function in elderly people who had a stroke. 70 participants did either Qigong or standard rehab for 12 weeks. Researchers measured breathing capacity, walking ability, and qua…

This study tested whether teaching COPD patients breathing exercises through short videos could reduce shortness of breath, increase activity, and improve sleep. Sixty adults with COPD followed a 30-day program of pursed-lip and diaphragmatic breathing, guided by a 5-7 minute vid…

This study tested whether a three-week aerobic exercise program could reduce PTSD symptoms and improve sleep in 82 adults who survived the February 2023 earthquake in Turkey. Participants were randomly assigned to either supervised exercise sessions or a control group. Researcher…

This study tested whether using virtual reality (VR) glasses for 30 minutes each evening could improve sleep quality, reduce anxiety, and stabilize vital signs in intensive care patients with COPD. Fifty patients were split into two groups: one received VR sessions for a week, th…

This study tested a short behavioral sleep program called Sleep Well! for children ages 1 to 5 in urban primary care clinics. Researchers wanted to see if families would find it useful and stick with it. The program included healthy sleep advice and tips to improve bedtime habits…

This study tested whether a 10-minute daily mindfulness session via a smartphone app could improve sleep and lower stress in healthy adults. 81 participants wore an Ōura Ring to track sleep and heart rate, and were randomly assigned to either the mindfulness program or a waitlist…

This study tested whether a combination of morning blue light and evening red light therapy could improve sleep in 20 adults with mild sleep complaints. Participants wore a wrist device to track sleep during a normal week and then during a week of light therapy. The goal was to s…

This study looked at whether it is safe for people with a tracheostomy (a breathing tube in the neck) to use a Passy Muir valve while sleeping. The valve helps them speak by redirecting air, but using it at night hasn't been well studied. Researchers monitored 33 patients in a lo…

This study tested a behavioral sleep treatment in 36 veterans who have PTSD, insomnia, and sleep apnea. The goal was to see if improving sleep also improves quality of life and daily functioning. Participants attended therapy sessions and reported their sleep and well-being throu…

This study tested whether a daily mix of plant protein and two herbs (ashwagandha and rhodiola) could improve sleep in 100 adults aged 35-70 with sleep troubles. Participants took either the supplement or a placebo for 30 days and reported their sleep quality daily. The goal was …

This study tested whether the drug acetazolamide can improve sleep-disordered breathing in 39 adults with chronic pain who use opioids. Participants took either the drug or a placebo for one week each. The goal was to see if the pill could reduce sleep apnea events as an alternat…

This study tested whether practicing pranayama breathing exercises for 15-20 minutes a day, 5 days a week for 8 weeks, could help adults aged 60 and older feel less stressed, sleep better, and enjoy a higher quality of life. Researchers compared 74 participants who did the breath…

This pilot study tested a non-drug device called Bioboosti to see if it could help people with insomnia sleep better. Twenty adults with insomnia used the device, and researchers measured changes in sleep quality and daytime sleepiness. The goal was to find a safe, drug-free opti…

This study tested a 12-week self-management program for university students with chronic fatigue. The program taught skills like goal setting, time management, and stress coping. Researchers measured changes in fatigue, sleep quality, resilience, and daily balance. The goal was t…

This study tested different doses of light therapy to see which works best for improving sleep in people with Parkinson's disease. 203 participants used either bright-white or dim-red light boxes at different times of day. The goal was to find the most effective dose to ease slee…

This study tested whether a gentle electrical current applied to the scalp (tDCS) can reduce symptoms of major depression, schizophrenia, OCD, generalized anxiety, and insomnia. 320 adults aged 16–65 received multiple sessions over weeks. Researchers measured symptom changes usin…

This study tested whether a 12-week nurse-led program could help people on hemodialysis feel better and function better. 220 patients were split into two groups: one got the extra program during dialysis sessions, and the other got standard care. The program included light exerci…

This study tested daridorexant, a sleep medication, in 166 teenagers aged 10 to 17 with chronic insomnia. Participants took one of three doses of the drug or a placebo each evening. Researchers measured changes in total sleep time using overnight sleep tests and monitored safety.…

This completed Phase 2 trial tested whether Neurexan, a homeopathic tablet, can improve sleep and reduce stress in 81 people with short-term insomnia. Participants took Neurexan or a placebo for 14 days. Sleep efficiency was measured using brain activity and other body signals, w…

This study tested whether a physical activity program delivered via telehealth could improve sleep in children with autism spectrum disorder (ASD) and reduce stress for their parents. 160 children aged 8-12 and their caregivers took part from home, using activity trackers and que…

This study tested whether the drug Lemborexant helps people with delayed sleep phase syndrome (a condition where your natural sleep time is much later than desired) fall asleep faster. 71 adults took either the drug or a placebo nightly for up to 2 years. The main goal was to see…

This phase 2 study tested an experimental drug called ALKS 2680 in 93 adults with narcolepsy type 2, a condition causing severe daytime sleepiness. Participants took either the drug or a placebo daily to see if it safely improved their ability to stay awake. The trial is now comp…

This completed study tested four different nutritional supplements against a placebo to see if they could improve sleep quality in healthy adults. A total of 376 people took part over 12 weeks. Researchers measured sleep quality, daytime function, and related symptoms like insomn…

This study tested whether acupressure—a gentle finger-pressure technique on specific body points—could improve sleep, quality of life, and reduce hopelessness in older adults living in a nursing home. Fifty people aged 65 and older took part, with half receiving acupressure three…

This study tested a stepped-care telehealth program for cancer survivors living in rural areas who experience anxiety, depression, or sleep problems. Participants received either low-intensity check-ins or high-intensity phone therapy with a licensed therapist, depending on sympt…

This study tested an online sleep education program for young adult cancer survivors (ages 20-39) who have trouble sleeping. Participants took a single online session, with some also getting extra coaching. The goal was to see if it could reduce insomnia and improve mood. The stu…

This study tested whether installing special LED lights that mimic sunlight in hospital rooms could help treat depression and improve sleep. Fifteen adults with major depression participated. The goal was to see if the lights were comfortable and if they could reduce depression s…

This study tested whether a specially designed sleep cap could help infants in the neonatal intensive care unit (NICU) sleep longer and stay more stable. Fifty-three newborns over 32 weeks gestation wore the cap from 7 PM to 7 AM for three days while their sleep, heart rate, brea…

This early study tested a product called Chenghuang Circadian Rhythm Regulator in 15 adults with ongoing sleep problems. The goal was to see if it could improve sleep quality and immune markers. Results are not yet reported, but the study was small and had no comparison group.

This study tested whether virtual reality relaxation or binaural beat stimulation can improve sleep and reduce discomfort in 140 adults who had mechanical heart valve replacement. Many patients struggle with sleep due to the sound of the new valve. Participants were randomly assi…

This study followed 71 adults with narcolepsy who started taking LUMRYZ, a medication for excessive daytime sleepiness. Over 4 months, participants filled out questionnaires about their symptoms, how they felt about the drug, and their quality of life. The goal was to see if LUMR…

This study tested whether therapeutic touch — a gentle, non-invasive technique — can reduce pain, delirium, and improve sleep in 80 intensive care patients. Researchers measured pain, sedation, sleep quality, and vital signs like blood pressure and heart rate. The goal was to see…

This study tested a special sleep program for teenagers with ADHD who also have sleep problems. The program combines cognitive behavioral therapy with sleep tips and planning skills. Researchers wanted to see if better sleep could also improve ADHD symptoms and daily life. The st…

This study tested whether adding brief advice on the Mediterranean diet and physical activity to standard cognitive behavioral therapy for insomnia (CBT-I) could improve sleep quality. Five adults with chronic insomnia participated. Researchers measured sleep quality and insomnia…

This study tested a liposomal magnesium supplement in 60 adults who reported low energy and mood issues. Participants took the supplement daily for 14 days and filled out questionnaires about their energy, mood, and stress levels. The trial was small, short, and had no placebo gr…

This study tested a mobile health (mHealth) program designed to help people who have had a stem cell transplant for blood cancer get better sleep. Researchers wanted to see if the program was easy to use and if participants liked it. About 30 survivors, caregivers, and doctors ga…

This study tested whether an online program for insomnia (called SHUTi) could help heavy drinkers reduce their alcohol use. 113 adults who drank heavily and had trouble sleeping took part. The goal was to see if improving sleep would also lead to less drinking and fewer binge epi…

This study tested whether adding a virtual coach (phone support) helps veterans with insomnia use a digital cognitive behavioral therapy program for sleep. 244 veterans were randomly assigned to either the digital program with coaching or with minimal contact. The goal was to see…

This study tested an herbal compound in 108 adults who had trouble sleeping and tinnitus (ringing in the ears) but did not want to take sleeping pills. Participants took either a low dose, high dose, or placebo daily for 3 months. Researchers measured changes in sleep quality and…

This pilot study tested a brief cognitive behavioral therapy (CBT) program designed to help older adults (55+) safely reduce or stop their use of benzodiazepines, which are commonly prescribed for insomnia and anxiety but can be risky with age. Seventeen participants received the…

This study tested whether wearing a light-blocking eye mask at night (11 p.m. to 5 a.m.) could improve sleep quality and melatonin levels in 60 intensive care unit patients. Participants were randomly assigned to either wear the mask or receive standard care. Sleep quality was me…

This study tested whether a medication called lemborexant can help night shift workers sleep longer during the day. 29 full-time night shift workers who had trouble sleeping took either the drug or a placebo for two weeks. The goal was to see if the drug increased total daytime s…

This study tested whether a single online education session can help cancer survivors with insomnia sleep better. 70 survivors took part, learning either behavioral changes to improve sleep or relaxation techniques. The goal was to see if a simple, accessible program could ease i…

This completed Phase 2 trial tested whether a personalized mind-body program could improve sleep in 60 women aged 40–60 who work in healthcare and report short sleep. Participants tried 30-minute sessions of mindfulness, yoga, and guided walking in different orders over 12 weeks.…

This study tested a daily dietary supplement designed to improve sleep in women aged 40 to 65 going through menopause. 128 women with moderate sleep problems were randomly assigned to take either the supplement or a placebo for about three weeks. Sleep quality, nighttime awakenin…

This study tested whether two types of gentle exercise—stretching or traditional pregnancy exercises—could improve sleep quality in pregnant women during their third trimester. Sixty women with sleep troubles took part in guided sessions twice a week for three weeks. The goal was…

This study tested a new automatic setting (Auto-EPAP) on a ventilator to see if it could better manage airway blockages during sleep compared to the standard manual setting. It involved 23 adults with conditions like sleep apnea, COPD, or obesity-related breathing problems who al…

This study tested a drug called solriamfetol in 59 adults with obstructive sleep apnea who also had trouble thinking clearly and felt very sleepy during the day. The goal was to see if the drug could improve cognitive function, like attention and processing speed. Participants to…

This study looked at whether two types of talk therapy—Behavioral Therapy and Cognitive Therapy—can help Gulf War Veterans who have trouble sleeping. Fifty veterans took part, and their sleep problems were measured using a standard questionnaire. The goal was to see which therapy…

This study tested whether inhaling lemongrass (as a vapor or from an inhaler) could reduce nicotine dependence and improve health markers in 200 adult smokers aged 18–30. Participants used lemongrass products or nothing (control) and provided blood samples and questionnaires. The…

This study tested whether a headband called Muse-S, which senses brain activity, could help midlife women with sleep problems like insomnia. Thirty-one women going through menopause wore the device at home. The goal was to see if it was practical and if it improved sleep quality …

This study tested whether custom mouthguards (splints) designed using a 3D jaw-tracking device called MODJAW work better than standard mouthguards for people with teeth grinding (bruxism) or jaw pain. 40 adults with mild-to-moderate symptoms wore either a personalized or standard…

This study tested whether an Apple Watch paired with a special app and weekly health coaching could help dementia caregivers improve their sleep and mood. Twenty-one caregivers wore the watch to track their activity and sleep, and received personalized feedback and motivational c…

This study tested whether aromatherapy foot massage can reduce pain, improve sleep, and speed recovery after laparoscopic gallbladder removal. 103 adults received two 10-minute foot massages with essential oils after surgery. Researchers measured pain, sleep quality, and recovery…

This study tested an app called EMPOWER-ED that provides education and tools to help veterans reduce or stop taking benzodiazepines (like Xanax or Ativan). Long-term use of these drugs can lead to dependence and other risks. The study enrolled 170 veterans who had been taking ben…

This study tested whether a digital program called Sleepio, which provides cognitive behavioural therapy for insomnia, could be used by people with mild cognitive impairment or mild dementia. Thirty participants were enrolled to see if the program was acceptable and easy to use. …

This study tested three ways to manage sleep bruxism (teeth grinding) in 48 people with implant-supported dentures. One group got Botox injections into the jaw muscles, another used a custom mouth splint at night, and a third simply removed their dentures at night (control). Rese…

This study tested a new sleep medication called daridorexant in 164 adults and elderly people with insomnia. Participants received either the drug or a placebo for 4 weeks. Researchers measured changes in total sleep time, how fast they fell asleep, and time awake after sleep ons…

This early study tested whether the drug acetazolamide can reduce breathing pauses during REM sleep in people with obstructive sleep apnea who cannot use a CPAP machine. Eleven participants took either the drug or a placebo for a few nights. Researchers measured breathing events …

This pilot study tested a program called Sleep-SMART for veterans aged 60 and older who have both mild cognitive impairment (MCI) and insomnia. The program combines standard insomnia therapy with memory-support strategies to help participants learn and stick with the treatment. R…

This small pilot study tested whether cannabis oil (with different ratios of CBD to THC) could help with insomnia in people who also have major depression. Fourteen adults took either a high-CBD oil, a low-CBD oil, or a placebo for a short time. The main goal was to see if a larg…

This study tested different treatments for sleep problems caused by Long COVID. It included 830 adults who had COVID-19 and now have trouble sleeping or feel very sleepy during the day. The goal was to see if treatments matched to specific sleep issues could help people feel bett…

This study tested a special sleep program for 40 people who recently lost their spouse or long-term partner. The program used online sessions to teach better sleep habits and was compared to just giving information. The goal was to see if it could improve sleep and reduce inflamm…

This study looked at whether teaching people with type 2 diabetes about good sleep habits can improve their sleep quality and blood sugar control. One hundred adults with type 2 diabetes and poor sleep took part. Half received sleep hygiene education and kept a sleep diary for tw…

This study tested whether providing overnight infant care and parenting support helps new mothers with substance use disorder living in residential treatment programs. 41 mothers participated, and researchers measured how many enrolled, completed the program, and gave feedback. T…

This study looked at whether placing small tubes in the ears of children aged 1-4 with chronic ear fluid (otitis media with effusion) improves their sleep and quality of life. Sixty children were randomly assigned to either receive ear tubes or not. Sleep was measured with a wris…

This study tested if an app that teaches better sleep habits could help people with long-term pain and insomnia. 105 adults in a 4-week rehab program either got the app or standard care. The goal was to see if the app improved sleep quality more than rehab alone.

This completed VA study tested two ways to help more veterans with chronic insomnia get brief behavioral treatment (BBTI) in primary care clinics. Over 277,000 veterans were included across four VA medical centers. The study compared training providers alone versus training plus …

This study tested whether an 8-week mindfulness-based stress reduction program could lower stress, anxiety, depression, and cortisol levels in infertile women. 84 women participated, with half taking the program and half serving as a control group. The goal was to see if mindfuln…

This study tested whether a culturally adapted version of cognitive behavioral therapy for insomnia (CBTi) could help Arab adults sleep better. 54 participants were randomly assigned to receive one of two adapted therapy versions or be placed on a waitlist. The goal was to see if…

This study tested whether giving children a single oral dose of steroid right after tonsillectomy can reduce pain and lower the need for strong painkillers. It involved 163 children aged 3 to 12 having outpatient tonsil surgery. Researchers measured pain scores and opioid use for…

This study tested whether orofacial myofunctional therapy (OMT) — simple tongue and throat exercises done during the day — can improve breathing during sleep in people with mild-to-moderate sleep apnea. 209 adults with sleep apnea participated, comparing OMT to a placebo exercise…

This study tested whether interactive game-supported sleep hygiene training could improve sleep quality, menopausal symptoms, and quality of life in menopausal women. 82 women aged 40-60 with poor sleep took part. They received four sleep hygiene lessons paired with a digital gam…

This study tested whether a self-applied ear massage, done twice daily for two weeks, could improve sleep quality in 60 women affected by the earthquake in Hatay. Participants used a sleep tracker and filled out questionnaires to measure changes. The goal was to see if this simpl…

This study looked at whether teaching healthy habits to pregnant women could improve their sleep and physical activity. Fifty-seven women in their third trimester took part. One group received six weeks of health training, while the other group had standard care. Results showed t…

This study tested whether an internet-based cognitive-behavioral therapy program (iCBT-I) can help people with chronic insomnia. 107 adults were randomly assigned to receive the online program or usual care. The program included educational videos, sleep tracking, and techniques …

This study tested an online insomnia treatment program for adult survivors of childhood cancer. Over 1,500 survivors participated, using a web-based program that teaches healthy sleep habits and cognitive behavioral techniques. The goal was to see if improving sleep could also bo…

This study tested whether taking a 15-20 minute power nap each day for six weeks could improve sleep quality, reduce depression symptoms, and lower stress in healthy workers. Forty volunteers, including both daytime and shift workers, participated. Researchers measured changes us…

This study tested whether taking rosemary and daylily extracts can improve sleep in adults over 50 who have trouble falling asleep. Ten participants took either a low or high dose of the herbal supplement or a placebo for eight weeks. The goal was to see if the supplements could …

This study tested whether laughter yoga—a practice combining laughing exercises and breathing techniques—can reduce fatigue, improve sleep quality, and boost psychological well-being in people with multiple sclerosis. Forty MS patients participated, with one group doing laughter …

This 12-week study tested whether combining acupuncture, yoga, and gradual medication reduction can help adults aged 65 and older lower their use of benzodiazepines (medications for anxiety and insomnia). Twenty-three participants received weekly acupuncture, private yoga classes…

This study tested whether elastic therapeutic taping can reduce pain after open-heart surgery (CABG). 195 patients were randomly assigned to receive real tape, placebo tape, or another supportive treatment near the surgical site. Neither patients nor researchers knew who got whic…

This study tested whether using virtual reality (VR) during wound dressing changes can reduce pain and improve sleep in adults with moderate to severe burns. Sixty patients took part, and the researchers compared VR to standard care. The goal was to see if VR could make a painful…

This study tested a six-month exercise program that combines acupunch moves with SPOZ technology in 142 older adults with dementia. The goal was to see if it could improve balance, strength, and daily living skills. Participants did the program at adult daycare centers, and resea…

This study tested whether a combination of a specific jaw muscle technique and neck exercises could reduce pain and improve jaw function in people with temporomandibular disorder (TMD) and teeth grinding (bruxism). Sixty adults with TMD and bruxism were split into two groups: one…

This study looked at whether a physiotherapist-given baby massage could help infants aged 0-6 months sleep longer and strengthen the emotional bond with their mothers. Twenty-four healthy full-term babies received classical massage. Researchers measured sleep quality and mother-b…

This study tested a mobile app called SleepFix that provides digital behavioral therapy for insomnia in 128 older adults aged 50+ who also had mild memory concerns. Participants either used the app or received online sleep health education. The goal was to see if the app could re…

This study tested a smartphone app that teaches older adults (60+) simple behavioral tricks to fall asleep faster and stay asleep longer. 270 participants used either the app or received online sleep tips. The goal was to see if the app could reduce insomnia symptoms more effecti…

This study looks at how good or poor sleep quality influences quality of life, depression, and fatigue in people with multiple sclerosis. Researchers will survey about 121 adults with MS to measure their sleep patterns and link them to these health outcomes. The goal is to better…

This study examines whether ticagrelor, a heart medication, changes how the body absorbs and processes YZJ-1139, an experimental insomnia treatment. Healthy volunteers aged 18 to 45 will take YZJ-1139 alone and then with ticagrelor to compare drug levels and safety. The goal is t…

This study looks at whether a 90-minute afternoon nap, a moderate dose of caffeine, and a short recovery routine (stretching plus a snack) can improve evening athletic performance. Sixty elite university athletes (30 men, 30 women) will try different combinations of these strateg…

This study examines whether a new insomnia drug, YZJ-1139, can be safely taken with the antidepressant escitalopram. Healthy adults aged 18 to 45 will receive both drugs and be monitored for side effects, drug levels in the blood, and changes in eye movements, balance, and thinki…

This study examines how the sleep aid YZJ-1139 behaves in people with severe kidney impairment compared to those with normal kidney function. Sixteen adults will receive a single 20 mg dose, and researchers will measure drug levels in the blood and urine, as well as any side effe…

This study looks at a nerve in the neck called the ansa cervicalis, which controls muscles that help keep the airway open. Researchers will measure the nerve's size and shape in 50 adults having neck surgery for head and neck cancer. They will also test how stimulating the nerve …

This study looked at how children with cerebral palsy, their parents, and healthcare professionals experience sleep disordered breathing and its management. Researchers interviewed 24 participants to understand the challenges and what helps or hinders treatment. The goal was to g…

This study tested whether bright light in the afternoon, alone or with morning light, can shift teens' internal body clocks earlier. 84 adolescents aged 18-20 followed a stable sleep schedule and then lived in a lab for a week. Researchers measured melatonin levels to track clock…

This study looked at jaw disorders and teeth grinding in 76 elite basketball referees compared to healthy people. Referees face high stress and often hold a whistle between their teeth, which may strain the jaw. Researchers used ultrasound to measure jaw muscle thickness and foun…

This study looked at how sleep quality and beliefs about sleep affect the risk of relapse in people recovering from alcohol dependence. Researchers followed 198 adults as they left inpatient rehab and returned home, measuring sleep with questionnaires and activity monitors. The g…

This study looked at how two types of exercise—high-intensity interval training (HIIT) and continuous moderate exercise—affect sleep and inflammation in 52 older adults with HIV. Participants exercised three times a week for 16 weeks. Researchers measured sleep quality through su…

This study looks at how getting too little sleep and not putting weight on one leg affects muscle strength and balance. Healthy adults who exercise regularly will walk on one leg and sleep either 5 or 9 hours for three days. Researchers will measure muscle size, strength, and how…

This study investigates why people develop obstructive sleep apnea (OSA) and whether the underlying cause affects how they respond to different treatments. Researchers will test three approaches—CPAP, a sleep medication (eszopiclone), and supplemental oxygen—in adults with OSA. T…

This study looks at how not getting enough sleep and being awake at odd hours affects your thinking, blood chemistry, and the helpful bacteria in your gut. Researchers gave 55 healthy adults a prebiotic supplement or a placebo to see if it could help counter the negative effects.…

This study looked at how sleep quality improves when people with obstructive sleep apnea start using a CPAP machine. Researchers used a special headband to track deep sleep at home for 7 nights before and 9 nights after starting treatment. The goal was to see how quickly sleep ge…

Sleep problems affect up to 90% of people with alcohol dependence and often lead to relapse. This study tests whether a short questionnaire called the Short Sleep Index (SSI) can reliably measure sleep quality compared to a longer, standard sleep questionnaire. Researchers will a…

This study looked at nearly 2,000 people from the community to understand how depression, anxiety, and migraine are passed down through families. Researchers interviewed family members of all ages, including children as young as 8, to track patterns of these conditions over time.…

This study tested whether eating 28 grams of pistachios (about 40 nuts) one hour before bedtime could help regulate the body's internal clock in 28 overweight young adults. Researchers measured melatonin levels, antioxidant activity, and sleep-wake patterns. The goal was to see i…

This study surveys anesthesiologists to explore whether feelings of being a fraud (impostor phenomenon) are linked to everyday memory and attention lapses. Participants complete online questionnaires about impostor feelings, cognitive failures, anxiety, depression, sleep quality,…

This study compared 80 women with and without fibromyalgia to measure muscle strength, muscle thickness, vitamin D levels, and sleep quality. Researchers used advanced tools like isokinetic dynamometers and ultrasound to find differences between the groups. The goal was to better…

This study looked at 69 people with Parkinson's disease to see if sleep quality is linked to thinking skills and disease severity. Participants completed tests of sleep, memory, attention, and movement in one session. The goal is to better understand how these factors relate, whi…

This completed study looked at 1,740 newly married couples to see if the bacteria in their mouth, eyes, and gut are linked to sleep problems, vision issues, and mood. Participants provided samples and completed surveys about sleep, anxiety, depression, and dry eye symptoms. The g…

This study tested whether taking salt with breakfast versus dinner changes blood pressure patterns and nighttime salt excretion in 53 obese adults. Participants took salt tablets at different times of day. The goal was to see if timing affects blood pressure rhythms and related h…

This study explored sleep disorders in 37 adults with non-small cell lung cancer. Participants filled out questionnaires about their sleep, symptoms, mood, and quality of life. The goal was to create a guide to help doctors diagnose and treat sleep issues in this group, ultimatel…

This study tested whether helping people sleep longer (through sleep hygiene and extending sleep time) could lower their blood pressure during sleep. 66 adults who slept less than 7 hours per night took part. Researchers measured blood pressure during sleep and awake periods at t…

This early study tested whether a small electrode placed near the nerve that controls tongue movement could help people with obstructive sleep apnea. Fourteen adults who already needed surgery took part. The main goal was to see if the approach was safe and could make the tongue …

This study tested whether stimulating certain nerves or muscles in the throat can improve breathing in people with obstructive sleep apnea. Researchers placed temporary electrodes and measured airflow during sleep in 35 adults. The goal was to see if this approach is feasible and…

This early study tested whether a small electrode placed near the tongue nerve could be safely used in people with obstructive sleep apnea. 14 adults who could not use CPAP took part. The goal was simply to see if the nerve could be reached and stimulated, not yet to treat the co…

This study looked at whether being physically active can lessen the negative effects of poor sleep on the heart, thinking, and well-being. Researchers compared active and sedentary adults before and after three nights of reduced sleep. The goal is to understand if regular aerobic…

This study looked at the medical records of one person from a sleep clinic to see if their breathing problems were due to a condition called dysanapsis (where airways are smaller than normal) rather than true asthma. The goal was to better understand why some people with sleep ap…

This study tested a medical device called CAVA that uses electrodes on the face to record eye movements during sleep. Nine volunteers wore the device along with standard sleep monitoring equipment in a sleep lab. The goal was to see if CAVA could accurately classify sleep stages …

This study tested a special bassinet designed to keep mother and baby together safely after birth. 160 new mothers used either the new Couplet Care bassinet or a standard one. Researchers surveyed mothers about sleep, breastfeeding, and satisfaction, and reviewed medical charts. …

This study looked at how sleeping at high altitude (3600 m) affects breathing in healthy women, and whether the phase of their menstrual cycle makes a difference. 91 women spent two nights at altitude while their oxygen levels and breathing patterns were measured. The goal was to…

This study looked at 103 adults with narcolepsy or obstructive sleep apnea to see if anxiety, social, or work factors affect their ability to stay awake during a standard test. Participants filled out an anxiety questionnaire before the test. The goal is to better understand why …

This study looked at how using a tablet in the evening affects young children's sleep and thinking skills. Researchers compared kids who used a tablet before bed with those who had no screen time. They measured changes in sleep timing, melatonin levels, and executive function. Th…

This study examined whether older adults with disrupted sleep or irregular daily rhythms show early brain changes linked to Alzheimer's disease. Researchers used wrist-worn activity monitors and brain MRI scans in 47 people over 65 without major memory problems. The goal was to s…

This completed study looked at whether practicing Orgasmic Meditation (OM) is associated with better sleep quality. 41 experienced OM practitioners tracked their sleep using a phone app for 30 nights. The study aimed to see if more OM sessions or experiencing orgasm during practi…

This study looked at 173 infants with myelomeningocele, a severe form of spina bifida, to see if the timing of their surgery (before or after birth) affects their risk for sleep-disordered breathing. Researchers used sleep studies to measure breathing problems and later checked t…

This study looked at 62 children with cerebral palsy (ages 2-18) and their primary caregivers to understand how the children's sleep problems relate to caregiver burden and mental health. Researchers used questionnaires to measure sleep quality in both children and caregivers, al…

This study looked at how eye pressure changes when breath-hold divers hold their breath. Forty divers had their eye pressure, oxygen levels, heart rate, and blood pressure measured before, during, and after holding their breath. The goal was to understand these changes and how th…

This completed pilot study in Yomitan Village, Okinawa tested three simple, low-cost approaches to reduce stress and encourage healthy habits in 45 adults with overweight or pre-metabolic syndrome. Participants were randomly assigned to receive health leaflets, wear functional cl…

This study looked at whether a 15-minute meditation practice called Shoonya meditation can help people stay sharp after a night without sleep. Researchers compared regular meditators to people who nap regularly, measuring brain activity, heart rate, and cognitive performance. The…

This study looked at 40 healthy women ages 18-35 to see if different phases of the menstrual cycle affect walking patterns, pelvic movement, and sleep quality. Participants were tested during early follicular, ovulation, and luteal phases using a special walkway sensor and a slee…

This study looked at 395 adults with obstructive sleep apnea to see if a new tool called the Baveno classification agrees with the standard sleep test (polysomnography) for deciding treatment. Researchers compared symptoms and health records against sleep lab results. The goal is…

This study looked at 194 university students aged 18-30 to see how smartphone and digital game addiction relates to physical activity, sleep quality, stress, fatigue, and muscle or joint pain. Participants filled out questionnaires about their habits and health. The goal is to un…

This study tested a new approach called DREAM, where Veterans at risk for sleep apnea could go straight to home sleep testing without an initial in-person clinic visit. Over 6,500 Veterans took part to see if this speeds up diagnosis and treatment. The goal is to make sleep apnea…

This completed study looked at whether chemicals in the blood (metabolomics) can help diagnose obstructive sleep apnea and track changes with treatment. Researchers analyzed stored blood samples from 388 people with and without sleep apnea, and also collected new samples from pat…

This study followed 59 nurses during their first year of work to see if night shifts harm bone health. Researchers measured bone density and markers of bone turnover in night shift nurses compared to day shift nurses. The goal was to understand if shift work increases the risk of…

This study looks at how stress and insomnia are connected. Researchers used driving simulations with stressful events to measure emotional reactions and sleep patterns in 15 women with and without insomnia. The goal is to understand how stress affects sleep and vice versa, which …

This completed study looked at sleep problems in over 1,100 children and adults with specific learning disabilities (like dyslexia or dyspraxia), with or without ADHD. Participants filled out online questionnaires about their sleep habits. The goal was to find out how common diff…

This study looked at how the drug modafinil affects driving ability in 27 people with narcolepsy or hypersomnia. Participants took modafinil or a placebo for five days, then completed both simulated and real driving tests. The goal was to see if the drug improves alertness and re…

This completed Phase 1 study looked at whether obstructive sleep apnea (OSA) might contribute to Alzheimer's disease. Researchers studied 182 older adults aged 65-85 with and without OSA, using brain scans and breathing tests. The goal was to understand how sleep disruptions like…

This study looked at 89 people — some with bruxism (teeth grinding) and some healthy — to see if there is a connection between the body's 'automatic' nervous system and the tightness, stiffness, and elasticity of the chewing muscles. Participants wore a chest strap to measure hea…

This study looked at whether a 30-minute daytime nap can help mentally tired endurance athletes feel better and think more clearly. Eleven male amateur athletes completed two sessions: one where they did mentally tiring tasks before napping, and another where they just napped. Re…

This completed study looked at how sleep apnea and other health problems like diabetes and high blood pressure affect pain after root canal treatment. 78 adults were divided into three groups: those with sleep apnea, those with diabetes or high blood pressure, and healthy people.…

This study tested whether a 20-minute session of gentle brain stimulation (tDCS) before an afternoon nap could improve sleep patterns linked to memory and thinking in healthy adults aged 60 and older. Twelve participants completed computer tasks, received either real or fake tDCS…

This study looked at 48 young adults (24 with bruxism, or teeth grinding, and 24 without) to understand how jaw function, posture, muscle stiffness, pain, stress, and sleep quality are connected. Researchers used special tools to measure posture, muscle tightness, and pain levels…

This completed study in Norway looked at whether delaying school start times by one to two hours on Mondays and Tuesdays helps high school students sleep longer, feel less sleepy during the day, and improve their mental health and grades. Over 580 first-year students participated…

This study tested whether playing short sound bursts in sync with brain slow waves during sedation with dexmedetomidine can enhance sleep-like brain activity. 18 healthy adults each experienced in-phase, anti-phase, and sham stimulation in repeated blocks. The goal was to see if …

This study tested whether smartphone notifications could improve mood, physical activity, and sleep in over 1,000 medical interns. Participants received daily mood, activity, or sleep notifications through a mobile app. The study measured mood scores, step counts, sleep duration,…

This study looked at 38 adults who usually sleep less than 6 hours a night. Researchers helped them increase their sleep to the recommended 7 hours and measured changes in blood chemicals and insulin sensitivity. The goal was to find biological markers that can tell if someone is…

This study looked at whether veterans with traumatic brain injury (TBI) and insomnia can reliably measure their internal body clock at home. Thirty-one veterans wore a wrist device for a week and collected saliva samples to track melatonin levels. The goal was to see if these hom…

This study looked at whether using a wearable device (like a fitness tracker) along with social media can help adults become more active and sleep better. 75 adults who had never used a wearable device before took part. The researchers measured changes in physical activity and sl…

This study followed 42 sprinters to see if doing plyometric exercises (like jumps) at least twice a week during winter preseason improved their race times and reduced leg injuries. Participants reported their best times and any health problems online. The goal is to understand if…

This study looked at 198 adults with non-metastatic gastrointestinal cancer to see if taking chemotherapy as a pill (oral) or through a vein (IV) affects sleep quality and depression. Researchers measured sleep and mood before treatment, at 45 days, and at 90 days using standard …

This study tested a mobile app designed to help teenagers with asthma learn about healthy sleep habits. 120 teens aged 14-17 with asthma used the app or were in a comparison group. Researchers measured changes in sleep knowledge, confidence, and daytime sleepiness to see if the a…

This study looked at whether a wearable device (Xiaomi Mi Band 8) can accurately detect sleep-related breathing disorders. About 300 adults wore the band during a standard overnight sleep test. Researchers compared the band's sleep-stage data with the hospital test to see if wear…

This study looked at 77 never-smokers newly diagnosed with lung cancer to see how many also have sleep apnea and whether sleep apnea affects their cancer outlook. Participants had a sleep test before starting cancer treatment. The goal is to understand if sleep apnea is a hidden …

This completed study tested two different PAP systems (machines, masks, and tubing) for obstructive sleep apnea. Thirty employees of the device maker used each system for a week and rated their experience. The goal was to gather feedback to guide future product improvements, not …

This study followed 520 French adults with central or mixed sleep apnea to see how a treatment called adaptive servo-ventilation (ASV) improved their sleep quality. Participants used a breathing device that adjusts pressure in real time. The goal was to measure changes in sleep q…

This study looked at 89 obese pregnant women to find out how common sleep apnea is and whether it is linked to high blood pressure, preeclampsia, or poor fetal outcomes. Participants had a sleep test (polysomnography) to detect apnea. The goal was to understand the connection and…

This study looked at how sleep health impacts recovery quality in 174 adults after hip or knee replacement surgery. Participants wore activity monitors and kept sleep diaries to track their sleep patterns. The goal was to see if poor sleep leads to worse recovery, helping doctors…

This study looked at how children ages 8 to 17 use smartphones and tablets, including social media and games, and how that relates to their mental health, sleep, and physical activity. Over 900 children and their parents used the Aura app and completed surveys for three months. T…

This study looked at whether regular outdoor horseback riding can improve leg strength, core stability, balance, sleep, and overall function in healthy adults. Researchers compared 64 people who rode horses outdoors at least once a week for six months with non-riders. They measur…

This study tested a computer system designed to help doctors more accurately diagnose and manage complex brain disorders like dementia, epilepsy, and sleep problems. Researchers collected health data from 635 people visiting specialty clinics, including healthy volunteers, to see…

This study placed 15 healthy volunteers in a natural cave with no access to time cues for 40 days. Researchers measured how their sense of time, sleep cycles, stress levels, and group coordination changed. The goal was to understand how humans adapt to extreme isolation and time …

This study looked at how often insomnia occurs in people hospitalized for psychiatric conditions. Researchers checked 427 patients at 11 hospitals in Switzerland and Germany. They also explored whether age, gender, or type of disorder made insomnia more likely.

This study looked at 102 people with multiple sclerosis to see how sleep quality relates to fatigue, body awareness, and arm and leg function. Participants were grouped by good or poor sleep, and their abilities were measured with tests like walking speed and a heartbeat counting…

This study looked at how having fibromyalgia changes body measurements and sleep patterns in people with obstructive sleep apnea. Researchers measured neck, waist, and hip sizes, and used sleep tests and ultrasound to compare 77 participants. The goal was to better understand the…

This study tested a sleep program for 4-6 year olds in their last year before kindergarten. The program included activities at school and online materials for parents. The goal was to see if the program was easy to use and if it helped children sleep better. 98 children took part…

This pilot study tested whether limiting food intake to an 8am-to-6pm window for four weeks could improve metabolic health and appetite regulation in 16 healthy adults. Participants ate freely during that window and fasted the rest of the time. The study measured changes in appet…

This study looked at whether treating obstructive sleep apnea (OSA) can also reduce pain and problems in the jaw and face, known as temporomandibular disorders (TMD). Forty-one adults with OSA but not yet on treatment were checked for TMD before starting therapy and again after a…

This study tested whether using an indoor air purifier changes health measures like heart rate, sleep, and oxygen levels. 42 healthy adults wore Apple Watches while using a real or fake (sham) air purifier at home. The goal was to see if cleaner air makes a short-term difference …

This study tested a website designed to help teenagers with narcolepsy or idiopathic hypersomnia and their families understand and improve social relationships. Twenty-five teens and their parents reviewed the website's content, which included animations, patient stories, and exp…

This completed study tested two different methods for positioning a dental sleep appliance used to treat obstructive sleep apnea. Eleven adults each tried both a standard forward-jaw technique and a technique based on saying certain sounds. The goal was to see if the speech-based…

This study looked at whether treating insomnia can reduce the risk of heart disease in people with PTSD. Researchers measured blood pressure, blood vessel health, and other heart risk factors in 140 adults aged 40-59. The goal was to see if improving sleep could also improve hear…

This study looked at 138 physical therapy students aged 18-30 to see if their eating habits, sleep quality, and stress levels are linked. Participants filled out three questionnaires about eating attitudes, sleep, and perceived stress. The goal was to understand how these factors…

This completed study enrolled 230 people with Parkinson's disease, a related sleep disorder, and healthy volunteers. Participants used a smartphone app to track their movements daily and underwent brain scans. Some also gave skin biopsies to test for a protein linked to Parkinson…

This study used smartwatches to compare sleep stages and total sleep time between 62 adults with sleep bruxism (teeth grinding) and healthy controls. Participants wore a smartwatch for 7 nights to collect sleep data. The goal was to see if smartwatches can help monitor sleep brux…

This study looked at 106 people with obesity who were scheduled for weight-loss surgery. Researchers measured how their upper airways behaved during sleep and used MRI scans to see if changes after surgery could explain why some develop obstructive sleep apnea and others do not. …

This study followed 18 adults with active ankylosing spondylitis who were starting anti-TNF therapy for the first time. Researchers measured their sleep quality using overnight sleep tests and a questionnaire, and tracked their daily step counts with a wearable device. The goal w…

This study looked at 149 adults with high blood pressure and insomnia to understand how poor sleep might raise the risk of heart disease. Researchers used a sleep therapy called CBT-I to see if improving sleep could lower nighttime blood pressure. The goal was to learn more about…

This study watched 225 people with solid tumors who got a drug called G-CSF during chemotherapy. G-CSF can cause bone pain. Researchers measured pain levels and tracked what treatments (like pain relievers or other methods) helped. They also checked quality of life, fatigue, mood…

This study looked at whether a special camera test done during sleep (called drug-induced sleep endoscopy) can help doctors choose the right non-CPAP treatment for people with obstructive sleep apnea. 35 adults who could not use CPAP took part. The goal was to see if this approac…

This completed pilot study looked at whether a quick, non-invasive eye scan (OCT angiography) can detect early blood vessel changes in the retina of people with obstructive sleep apnea. Researchers compared 166 adults with and without sleep apnea. The goal was to see if retinal i…

This study looked at whether infants aged 6 to 9 months with joint hypermobility (very flexible joints) have different sleep patterns than other babies. Researchers used a parent questionnaire to compare sleep duration, night wakings, and sleep problems between 60 infants with an…

This study looked at how the sleep hormone melatonin and a specific gene (MTNR1B) work together to control blood sugar. Researchers tested 23 healthy adults in a controlled lab setting. The goal was to understand why some people may have higher diabetes risk, which could lead to …

This study looked at how low oxygen levels (hypoxia) in people with obstructive sleep apnea affect the body's ability to use insulin. Researchers measured insulin resistance in the liver and fat tissue of 48 non-diabetic adults. The goal was to understand why some sleep apnea pat…

This study looked at 150 children and adults who had their tonsils removed using one of three surgical methods: BiZact, coblation, or bipolar. Researchers measured pain after surgery, how long the operation took, when patients could eat solid food again, and how much the devices …

This study looked at how a pill form of THC (dronabinol) affects sleep and thinking in 18 adults. Some participants used cannabis frequently (more than 3 times a week), while others rarely used it (less than 10 times ever). Researchers measured sleep stages, alertness, memory, an…

This study looked at 120 university students to see if their smartwatch step counts matched what they reported on a physical activity questionnaire. Participants wore an Apple Watch and filled out a short survey about their weekly activity. The goal was to understand if objective…

This study tested whether a personalized online program delivered through WeChat could help college students better balance their time across physical activity, sleep, and sitting. Fifty students aged 18-25 who did not meet healthy movement guidelines were randomly assigned to re…

This study looked at whether insomnia affects pain sensitivity in people with Irritable Bowel Syndrome (IBS). Researchers measured pain thresholds using a barostat procedure in 70 participants, including IBS patients with and without insomnia, healthy volunteers, and people with …

This study looked at whether sleeping at least an hour more each night for a week could help college students handle pain better. Thirty-six healthy young adults wore watches to track sleep and heart rate, and took pain tests (pressure and cold) before and after the sleep change.…

This study tested whether a structured nutrition education program could improve nursing students' nutrition knowledge, eating habits, physical activity, and sleep quality. Forty-two students took part in multiple educational sessions. Researchers measured changes right after the…

This small study tested whether placing a nerve stimulation lead in a different spot during a sleep apnea device implant could improve breathing. 29 adults with moderate to severe central sleep apnea took part. The goal was to see immediate changes in breathing and airway functio…

This study looked at how well the diaphragm works in people with obstructive sleep apnea (OSA). Researchers used ultrasound to measure diaphragm movement in 60 adults with OSA. The goal was to see if diaphragm function is linked to how severe the sleep apnea is.

This completed study tracked 132 children with obstructive sleep apnea who had their tonsils removed. Researchers recorded how many had breathing problems after surgery, especially those with other health issues. The goal was to create a simple flowchart to help doctors decide wh…

This completed study looked at how consistently 300 obese adults (BMI over 30) used positive airway pressure therapy for sleep-disordered breathing. Researchers tracked whether patients used the device at least 4 hours per night for 70% of nights within the first 90 days and agai…

This study looked at 40 adults who had a blood clot in their lungs (pulmonary embolism). Researchers compared those who also had sleep-disordered breathing (like sleep apnea) with those who did not. The goal was to see if sleep problems affect short-term recovery and the chance o…

This study looked at 24 people with high-altitude pulmonary hypertension who live above 2500 meters. Researchers measured their sleep breathing at 3200 meters and again after moving to 760 meters. The goal was to see if lower altitude improves oxygen levels and reduces breathing …

This study looked at how well smartphone apps and a special ring (Belun Ring) can measure sleep quality in adults getting braces or other orthodontic treatment. 52 people from Case Western Reserve University's dental clinic took part. They answered sleep questionnaires and used t…

This study used a very powerful 7 Tesla MRI to look for tiny brain changes in 15 people with idiopathic REM sleep behavior disorder (iRBD) compared to 15 healthy volunteers. iRBD is a sleep condition that often leads to Parkinson's disease years later. The goal was to find early …

This study looked at how specific tongue muscles help keep the airway open during sleep in people with obstructive sleep apnea. Researchers used a special camera during sleep-like sedation to measure airway collapse. The goal was to understand the mechanisms behind airway obstruc…

This completed study looked at how blood sugar levels affect sleep in 30 adults with cystic fibrosis-related diabetes. Participants wore devices at home to track glucose and sleep for 10 days. The goal was to see if this kind of remote monitoring is practical and to gather early …

This study looked at 74 physiotherapy students to see how their daily physical workload—like time spent sitting and standing—affects their posture. Researchers used a 3D back scanner and surveys to measure posture, activity levels, sleep, and burnout. The goal was to find risk fa…

This study looked at whether a 25-minute or 45-minute nap helps teenage soccer players run faster and feel less tired. Sixteen male players tried both nap lengths and a no-nap day. Results showed that napping improved agility and made exercise feel easier, but did not help them k…

This completed study with 40 participants explored factors that might predict obstructive sleep apnea in people with Down syndrome. Researchers used a range of assessments, including sleep studies, heart monitoring, and exercise tests, to identify early warning signs. The goal is…

This study looked at how sleep quality, when people eat, and gut bacteria are linked to obesity. Researchers tested a mobile app to help people make healthier lifestyle changes. The study included 133 adults with different body weights, including some with sleep apnea. The goal w…

This study looked at whether a nutrition and behavior change program could help reduce sleep apnea in people who are overweight or obese. About 400 adults took part, and researchers measured changes in sleep apnea risk, daytime sleepiness, and weight loss. The goal was to see if …

This study looked at 102 adults to see how common restless legs syndrome is in people with temporomandibular joint (jaw) disorders. Researchers also checked if having both conditions affects sleep quality and daily life. Participants filled out questionnaires about their symptoms…

This completed study looked at 825 adults with type 1 diabetes who use an insulin pump to see how many also have obstructive sleep apnea. Researchers used overnight oxygen tests and sleep studies to find cases. The goal was to understand if sleep apnea is linked to diabetes compl…

This study examined 180 young adults to see if the ratio of their index to ring finger length (2D:4D) is linked to joint hypermobility (being double-jointed). The idea is that this finger ratio may reflect hormone levels before birth. Researchers measured joint flexibility using …

This study looked at 200 heart transplant patients to see if the time of day the donor heart was removed affects how well the patient does. Researchers compared hearts taken during the body's rest phase (midnight to noon) versus the active phase (noon to midnight). They tracked s…

This completed study compared 72 adults with cervicogenic headache (headache from the neck) to healthy volunteers. Researchers used questionnaires to measure central sensitization (overactive pain signaling) and neuropathic pain (nerve pain). The goal was to see if these pain mec…

This study followed 127 first-time mothers to see if their sleep quality, anxiety levels, and nighttime phone use before labor were linked to how long labor lasted and whether they needed extra medical help. Participants filled out questionnaires during routine checkups, and rese…

This study looked at whether working night shifts for just three nights in a row can disrupt bone health. Twenty healthy adults aged 20-40 either followed a normal sleep schedule or stayed awake at night and slept during the day. Researchers measured bone turnover markers to see …

This study looked at whether rotating shift workers can stick to a time-restricted eating plan, where they only eat during certain hours. Researchers wanted to see if this approach is practical and how it affects blood glucose levels during day and night shifts. 31 healthcare wor…

This study followed over 200 sleep apnea patients from a large European database to see how many developed heart problems, metabolic issues, cancer, or died over time. Researchers also checked whether using CPAP therapy (a common sleep apnea treatment) affected these risks. The g…

This completed study looked at how common poor sleep is after a C-section when spinal morphine is used for pain relief. Researchers followed 286 mothers and measured sleep quality, pain, nausea, and itching on the first night after surgery. The goal was to understand which factor…

This study looks at how cardiac arrest affects thinking, memory, emotions, and sleep over time. About 200 survivors will take detailed brain tests 7 and 24 months after their cardiac arrest. Their results will be compared to heart attack patients who did not have a cardiac arrest…

This study looked at how the timing of sleep affects what teenagers eat. Researchers wanted to understand why getting more sleep helps some teens eat less, but not others. They studied 190 healthy teens aged 14-18 to see if matching sleep to their natural body clock improves thei…