Could your own blood help you heal faster after gum surgery?

NCT ID NCT07637838

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests whether applying platelet-rich fibrin (PRF) — a wound dressing made from a patient's own blood — to the roof of the mouth after gum graft surgery improves pain, sleep, and overall quality of life compared to standard dressings. About 78 adults needing gum surgery will be randomly assigned to receive either PRF or a commercial dressing. Participants will report their pain and quality of life at several time points over two weeks and wear a sleep tracker to measure sleep quality.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
platelet-rich fibrin (PRF)
What this could lead to
If it works, this could offer a simple, natural way to reduce pain and speed healing after gum surgery, improving patients' daily comfort and sleep.
What could go wrong
This is a small, early-stage trial (78 people) testing a specific surgical setting. Results may not apply to other procedures or populations, and PRF may not outperform standard dressings.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Air Force Post Graduate Dental School

    San Antonio, Texas, 78236, United States

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