Tiny study hints Anti-TNF may improve sleep in ankylosing spondylitis

NCT ID NCT07441239

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study followed 18 adults with active ankylosing spondylitis who were starting anti-TNF therapy for the first time. Researchers measured their sleep quality using overnight sleep tests and a questionnaire, and tracked their daily step counts with a wearable device. The goal was to see if these measures improved after 4 months of treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

anti-TNF therapy

What this could lead to

If successful, this could show that anti-TNF therapy improves sleep and daily activity in people with active ankylosing spondylitis.

What could go wrong

This is a very small pilot study with only 18 participants and no control group, so results may not apply to everyone. It only looks at short-term changes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ankylosing spondylitis insomnia Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.