Could a common antibiotic wake up the sleepy brain?

This study tests whether clarithromycin, an antibiotic, can reduce excessive daytime sleepiness in people with narcolepsy or idiopathic hypersomnia. Participants receive either clarithromycin or a placebo for 14 days. Researchers will measure changes in sleepiness, brain activity, inflammation, and gut bacteria to understand how the drug might work. The goal is to see if this antibiotic could be a new way to help people stay awake during the day.