IDIOPATHIC HYPERSOMNIA
Clinical trials for IDIOPATHIC HYPERSOMNIA explained in plain language.
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New drug TAK-360 tested for Long-Term safety in sleep disorders
Disease control Recruiting nowThis study looks at the long-term safety and tolerability of the drug TAK-360 in people with narcolepsy (type 1 or 2) or idiopathic hypersomnia — conditions that cause severe daytime sleepiness. Participants who completed a previous TAK-360 study can join and will continue taking…
Matched conditions: IDIOPATHIC HYPERSOMNIA
Phase: PHASE2, PHASE3 • Sponsor: Takeda • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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New sleep disorder drug ORX750 tested for Long-Term safety
Disease control Recruiting nowThis study is a long-term follow-up for people with narcolepsy or idiopathic hypersomnia who previously took the experimental drug ORX750. Researchers want to see if the drug remains safe and effective over time. About 90 participants will take ORX750 orally and be monitored for …
Matched conditions: IDIOPATHIC HYPERSOMNIA
Phase: PHASE2 • Sponsor: Centessa Pharmaceuticals (UK) Limited • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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New pill aims to fight excessive daytime sleepiness
Symptom relief Recruiting nowThis study tests a new drug called ALKS 2680 to see if it can safely reduce daytime sleepiness in people with idiopathic hypersomnia, a condition causing excessive sleepiness without clear cause. About 126 participants will receive either the drug or a placebo daily for 8 weeks. …
Matched conditions: IDIOPATHIC HYPERSOMNIA
Phase: PHASE2 • Sponsor: Alkermes, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 14:03 UTC
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New sleep drug study aims to help people who sleep too much
Symptom relief Recruiting nowThis study looks at how a low-sodium version of the drug oxybate affects total sleep time in adults with idiopathic hypersomnia, a condition causing excessive sleepiness. About 30 participants will use sleep trackers and special earbuds to measure sleep. The goal is to see if the…
Matched conditions: IDIOPATHIC HYPERSOMNIA
Phase: PHASE4 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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New sleepiness drug could change lives for narcolepsy and hypersomnia patients
Symptom relief Recruiting nowThis study tests a new drug called ORX750 (cleminorexton) in 248 adults with narcolepsy type 1, type 2, or idiopathic hypersomnia—conditions that cause severe daytime sleepiness. The drug mimics a natural brain protein that helps keep people awake. The main goals are to check saf…
Matched conditions: IDIOPATHIC HYPERSOMNIA
Phase: PHASE2 • Sponsor: Centessa Pharmaceuticals (UK) Limited • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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New hope for chronic sleepiness: phase 3 drug trial launches
Symptom relief Recruiting nowThis study tests an experimental drug called HBS-301 to see if it can reduce symptoms of idiopathic hypersomnia, a condition causing severe daytime sleepiness, trouble waking up, and fatigue. About 248 adults with moderate to very severe symptoms will receive either the drug or a…
Matched conditions: IDIOPATHIC HYPERSOMNIA
Phase: PHASE3 • Sponsor: Harmony Biosciences Management, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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New Orexin-Like pill could fight extreme daytime sleepiness
Symptom relief Recruiting nowThis Phase 2 trial tests TAK-360, a drug that mimics the brain chemical orexin, in 96 adults with idiopathic hypersomnia (IH). IH causes severe daytime sleepiness and trouble waking up, even after long sleep. Participants will receive either TAK-360 or a placebo to see if the dru…
Matched conditions: IDIOPATHIC HYPERSOMNIA
Phase: PHASE2 • Sponsor: Takeda • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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New pill shows promise for keeping people with narcolepsy awake longer
Symptom relief Recruiting nowThis study is testing the long-term safety and how well ALKS 2680 works over time in people with narcolepsy type 1, type 2, or idiopathic hypersomnia. Participants take a once-daily tablet at different doses. The goal is to see if the drug remains safe and effective for staying a…
Matched conditions: IDIOPATHIC HYPERSOMNIA
Phase: PHASE2, PHASE3 • Sponsor: Alkermes, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC
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Can your lunch make you sleepier? new study investigates Food-Sleep link in narcolepsy
Knowledge-focused Recruiting nowThis study looks at how eating affects sleepiness and nighttime sleep in people with type 1 narcolepsy, idiopathic hypersomnia, and healthy volunteers. Over 4 days, participants will log their meals, wear a glucose monitor, and track sleep with a headband and watch. The goal is t…
Matched conditions: IDIOPATHIC HYPERSOMNIA
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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Narcolepsy's hidden toll: study probes social brain in sleep disorders
Knowledge-focused Recruiting nowThis study looks at how narcolepsy (types 1 and 2) and idiopathic hypersomnia affect social cognition—skills like recognizing emotions and making decisions. Researchers will give 75 adults several questionnaires to measure attention, impulse control, empathy, and emotion recognit…
Matched conditions: IDIOPATHIC HYPERSOMNIA
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC