New sleep drug ORX750 tested for long-term safety in narcolepsy and hypersomnia patients

NCT ID NCT07096674

Recruiting now Symptom relief Sponsor: Centessa Pharmaceuticals (UK) Limited Source: ClinicalTrials.gov ↗

First seen Mar 27, 2026 · Last updated May 12, 2026 · Updated 9 times

Summary

This study looks at the long-term safety and effectiveness of a drug called ORX750 in people with narcolepsy (types 1 and 2) or idiopathic hypersomnia who have already completed a previous ORX750 study. About 90 participants will take the drug and be monitored for side effects and how well it controls their sleep symptoms. The goal is to see if ORX750 remains safe and helpful over a longer period.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Abington, Pennsylvania
RECRUITING

Abington, Pennsylvania, 19046, United States
Atlanta, Georgia
RECRUITING

Atlanta, Georgia, 30328, United States
Auburn, alabama
RECRUITING

Auburn, Alabama, 36832, United States
Austin, Texas
RECRUITING

Austin, Texas, 30328, United States
Bologna
RECRUITING

Bologna, BO, 40139, Italy
Cincinnati, Ohio
RECRUITING

Cincinnati, Ohio, 45245, United States
Denver, North Carolina
RECRUITING

Denver, North Carolina, 28037, United States
Dublin
RECRUITING

Dublin, Ohio, 43017, United States
El Paso, Texas
RECRUITING

El Paso, Texas, 79912, United States
Hendersen, Navada
RECRUITING

Henderson, Nevada, 89052, United States
Henderson, Nevada
RECRUITING

Henderson, Nevada, 89052, United States
Huntersville, North Carolina
RECRUITING

Huntersville, North Carolina, 28070, United States
Miami, Florida
RECRUITING

Miami, Florida, 33176, United States
Móstoles, Madrid
RECRUITING

Móstoles, Madrid, 28938, Spain
North Charleston, South Carolina
RECRUITING

North Charleston, South Carolina, 29406-9196, United States
Orlando, Florida
RECRUITING

Orlando, Florida, 32807, United States
Santa Ana, California
RECRUITING

Santa Ana, California, 92705, United States
Sterling Heights, Michigan
RECRUITING

Sterling Heights, Michigan, 48314, United States
Stockbridge, GA
RECRUITING

Atlanta, Georgia, 30281, United States
Toronto
RECRUITING

Toronto, Ontario, M5S 3A3, Canada
Verona
RECRUITING

Verona, VR, 37134, Italy
Willow Grove, Pennsylvania
RECRUITING

Willow Grove, Pennsylvania, 19090, United States
Winter Park, FL
RECRUITING

Winter Park, Florida, 32789, United States
Álava, Spain
RECRUITING

Álava, 01004, Spain

Conditions

Explore the condition pages connected to this study.

IDIOPATHIC HYPERSOMNIA NARCOLEPSY TYPE 1 NARCOLEPSY TYPE 2