Centessa Pharmaceuticals (uk) Limited

This study continues testing the safety and effectiveness of ORX750 medication for people with narcolepsy or idiopathic hypersomnia who completed an earlier trial. It follows 90 participants to monitor long-term side effects and whether the drug continues to help with daytime sle…

This study is testing a new drug called ORX750 in people with narcolepsy or idiopathic hypersomnia, conditions that cause severe daytime sleepiness. The main goals are to see if the drug is safe and how the body processes it. Researchers also want to find out if it can help peopl…

This is an early-stage study to test the safety of a new drug called ORX142 for people who struggle with excessive daytime sleepiness. Researchers will give the drug to healthy adults, including some who are sleep-deprived, to see how their bodies handle it and if it helps them s…

This is an early-stage study to check the safety of a new oral drug called ORX489 in healthy adults. Researchers will give single and multiple doses to see how the body handles the drug and if it helps people stay awake. The main goal is to understand the drug's side effects and …