Poor sleep in seniors linked to brain changes that may precede Alzheimer's

NCT ID NCT04044495

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study examined whether older adults with disrupted sleep or irregular daily rhythms show early brain changes linked to Alzheimer's disease. Researchers used wrist-worn activity monitors and brain MRI scans in 47 people over 65 without major memory problems. The goal was to see if sleep issues could serve as an early warning sign for cognitive decline.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this study could help identify early warning signs for Alzheimer's disease based on sleep patterns, potentially leading to preventive strategies.
What could go wrong
This is an observational study with only 47 participants, so results may not apply to everyone. It looks for associations, not causes, and cannot prove that sleep changes lead to Alzheimer's.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU de Bordeaux

    Bordeaux, 33 076, France

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