Botox vs. splints: which stops teeth grinding best for denture wearers?
NCT ID NCT07361900
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested three ways to manage sleep bruxism (teeth grinding) in 48 people with implant-supported dentures. One group got Botox injections into the jaw muscles, another used a custom mouth splint at night, and a third simply removed their dentures at night (control). Researchers measured muscle activity and denture retention over 12 months to see which approach worked best.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Botulinum toxin type A (Botox)
- What this could lead to
- If Botox works better than splints or no treatment, it could offer a simple injection to reduce teeth grinding and improve denture fit.
- What could go wrong
- This is a small, early-phase study with only 48 people. Botox may not work for everyone, and effects are temporary, requiring repeat injections.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for BRUXISM are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Delta University for Science and Technology
Gamasa, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can botox beat ibuprofen for jaw pain from teeth grinding?
- Do wind instruments cause more jaw pain? survey targets amateur musicians
- Hands-On therapy plus pilates may unlock relief for teeth grinders
- Could spit reveal the stress behind teeth grinding?
- Face shape may predict botox success for teeth grinders
- Sniff away your jaw pain? essential oils tested for bruxism