Can a sleep drug boost metabolic health in menopausal women?

NCT ID NCT05593653

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether the sleep medication suvorexant (Belsomra) can reduce insomnia severity and improve metabolic health in midlife women who have both insomnia and signs of metabolic syndrome. Thirty-one healthy women aged 40-65 who were perimenopausal or postmenopausal took either suvorexant or a placebo for 4 weeks. Researchers measured changes in insomnia scores and fasting glucose levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Suvorexant (Belsomra)

What this could lead to

If it works, this could point toward a treatment that eases insomnia and improves metabolic health in midlife women.

What could go wrong

This is a small, completed Phase 4 trial with only 31 participants, so results may not apply widely. The drug may not significantly improve metabolic outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome insomnia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States