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Can a light box help Parkinson's patients sleep better?

NCT ID NCT04291014

Completed Symptom relief Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested different doses of light therapy to see which works best for improving sleep in people with Parkinson's disease. 203 participants used either bright-white or dim-red light boxes at different times of day. The goal was to find the most effective dose to ease sleep problems and fatigue.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
SunRay light boxes (light therapy device)
What this could lead to
If it works, this could point toward a simple, non-drug way to improve sleep and reduce fatigue in Parkinson's disease.
What could go wrong
This is a completed dose-finding study, not a proof of effectiveness. The results may not show clear benefit, and light therapy might not work for everyone or could be inconvenient to use daily.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Fatigue Parkinson disease sleep disorder sleep-wake disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FATIGUE PARKINSON DISEASE SLEEP DISORDER

Contacts and locations

Locations

  • Barrow Neurological Institute

    Phoenix, Arizona, 85013, United States

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Mount Sinai - Icahn School of Medicine

    New York, New York, 10029, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Ohio State University

    Columbus, Ohio, 43221, United States

  • SUNY Stonybrook

    Stony Brook, New York, 11794, United States

  • SUNY Upstate

    Syracuse, New York, 13210, United States

  • UC Davis

    Sacramento, California, 95817, United States

  • UC Irvine

    Irvine, California, 92697, United States

  • University of Alabama

    Birmingham, Alabama, 35233, United States

  • University of Cincinnati

    Cincinnati, Ohio, 45219, United States

  • University of Iowa

    Iowa City, Iowa, 52242, United States

  • University of Miami

    Miami, Florida, 33136, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19107, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15213, United States

  • University of Rochester

    Rochester, New York, 14642, United States

  • University of Utah

    Salt Lake City, Utah, 84132, United States

  • University of Virginia

    Charlottesville, Virginia, 22903, United States

  • Vanderbilt University

    Nashville, Tennessee, 37232, United States

  • Wake Forest University

    Winston-Salem, North Carolina, 27104, United States

  • Washington University in St. Louis

    St Louis, Missouri, 63110, United States

  • Weill Cornell

    New York, New York, 10021, United States

  • Yale University

    Fairfield, Connecticut, 06824, United States

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