Botox vs. mouthguards: which eases grinding pain best?

NCT ID NCT07586072

Completed Symptom relief Sponsor: Recep Tayyip Erdogan University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 2 times

Summary

This study tested three ways to treat jaw pain caused by teeth grinding (bruxism): a custom mouthguard (occlusal splint), Botox injections, or both together. Sixty adults completed the 3-month trial. Researchers measured pain and jaw function changes to see which approach worked best.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Botulinum toxin type A (Dysport)
What this could lead to: If successful, this could show which treatment—splint, Botox, or both—works best for easing jaw pain and clenching symptoms.
What could go wrong: This is a small, non-randomized study, so results may not apply to everyone. Botox injections can cause temporary muscle weakness or bruising.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bruxism myofascial pain syndrome temporomandibular joint disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRUXISM MYOFASCIAL PAIN TEMPOROMANDIBULAR DISORDERS (TMD)

Contacts and locations

Locations

Recep Tayyip Erdogan University Faculty of Dentistry

Rize, Rize Province, 53020, Turkey (Türkiye)

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