Circadian rhythm sleep disorder, shift work type
MONDO:0024382A circadian sleep disorder that occurs when work schedules force people to be awake when their circadian rhythms dictate that they should be sleeping. It is classified as a Circadian Rhythm Disorder (CRD) and is extrinsic, i.e. caused by external behavioral factors.
Also known as: circadian rhythm sleep disorder of shift work type, shift work disorder
50 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Eating only at certain times may protect night shift workers from heart disease
Disease control Recruiting nowThis study looks at whether time-restricted eating (eating only during certain hours) can improve blood pressure and insulin sensitivity in people who work night shifts. Night shift workers are at higher risk for heart disease and type 2 diabetes. Researchers will compare 4 weeks…
Phase: NA • Sponsor: Colorado State University • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Could a wearable device replace hospital sleep tests for kids with cerebral palsy?
Diagnosis Recruiting nowThis study is testing whether simple wearable devices can accurately screen for sleep disorders in children with cerebral palsy. About 140 children aged 6 to 15 will wear the devices at home and then undergo a standard hospital sleep test. The goal is to see if the wearable metho…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Diagnosis
Last updated Jun 27, 2026 14:02 UTC
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Meal timing may shield night shift workers from disease
Prevention Recruiting nowThis study looks at whether adjusting meal timing can reduce health risks for night-shift nurses and nursing assistants who are overweight. Participants will either just track their diet, follow a 10-hour daytime eating window, or add a low-sugar snack during night shifts. The go…
Phase: NA • Sponsor: Salk Institute for Biological Studies • Aim: Prevention
Last updated Jun 27, 2026 08:04 UTC
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Medical cannabis under the microscope: 1,000 patients tracked for Real-World relief
Symptom relief Recruiting nowThis study follows 1,000 adults in Canada who are authorized to use medical cannabis for pain, sleep issues, anxiety, depression, or epilepsy. Researchers will track changes in symptoms using standard questionnaires over 24 weeks. The goal is to see how well medical cannabis work…
Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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New app aims to fix night shift sleep problems
Symptom relief Recruiting nowThis study tests a mobile app called SHIFT that uses data from an Apple Watch to give personalized light exposure advice, helping night shift workers sleep better. Researchers will enroll 300 night shift workers who have poor sleep. The goal is to see if the app improves sleep, h…
Phase: NA • Sponsor: Henry Ford Health System • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Can a 4-Week online course tame your night terrors?
Symptom relief Recruiting nowThis study tests a 4-week online course designed to help adults who experience parasomnias—unwanted sleep events like sleep terrors, sleepwalking, and nightmares. The course teaches safety planning, relaxation, and therapy techniques. Researchers will measure whether it reduces h…
Phase: NA • Sponsor: University of Manitoba • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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New drug aims to keep night shift workers awake and safe
Symptom relief Recruiting nowThis Phase 3 trial tests whether the drug solriamfetol can reduce excessive sleepiness in people with shift work disorder. About 520 adults who work night shifts will take either solriamfetol or a placebo daily for 12 weeks. The study measures how well they stay awake and their o…
Phase: PHASE3 • Sponsor: Axsome Therapeutics, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Memory tricks may help older adults finally get a good Night's sleep
Symptom relief Recruiting nowThis study tests whether a special memory support program can help people aged 50 and older remember and stick to their sleep treatment. The program uses simple memory strategies alongside standard sleep therapy. Researchers will track sleep quality, daily functioning, and life s…
Phase: NA • Sponsor: University of California, Berkeley • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Amino acid supplement tested for better sleep in brain injury
Symptom relief Recruiting nowThis study tests whether taking branched chain amino acids (BCAAs) twice a day for three weeks can improve sleep in people with traumatic brain injury. Researchers will also check if the supplement is easy to take and if participants stick with it. The study involves 300 veterans…
Phase: NA • Sponsor: Portland VA Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Night shift Workers' metabolism under the microscope
Knowledge-focused Recruiting nowThis study aims to understand how working night shifts impacts blood sugar, fat levels, and heart health in hospital staff. Researchers will compare workers who do night shifts with those who don't, using continuous glucose monitors and other measurements. The goal is to gather k…
Sponsor: Olga Ramich (formerly Pivovarova) • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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Power nap prescription: study tests best nap length for night shift workers
Knowledge-focused Recruiting nowThis study looks at whether taking a nap during a night shift can improve blood pressure and alertness in healthcare and public safety workers. Researchers will compare naps lasting 0, 15, 30, 45, or 60 minutes taken at 2:00 AM. The goal is to find the nap length that best balanc…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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New study aims to fix sleep tracking for nightshift workers
Knowledge-focused Recruiting nowThis study aims to improve how sleep is measured for nightshift workers, whose inverted schedules make standard sleep trackers inaccurate. Researchers will use an Apple Watch along with machine learning to better detect daytime sleep. About 100 nightshift workers will participate…
Phase: NA • Sponsor: Henry Ford Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Late shifts and downtime at work could fuel problem gambling, new study suggests
Knowledge-focused Recruiting nowThis study looks at whether working unusual hours or having idle time at work makes people more likely to gamble in risky ways. Researchers will interview 25 adults who currently have or have had gambling problems and who have worked in the past year. The goal is to understand ho…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Midnight meals: could a simple food delivery steady blood sugar for night-shift heroes?
Knowledge-focused Recruiting nowThis study looks at whether providing meals to night-shift EMS workers can help them keep steady blood sugar levels. Forty participants will receive a meal service and track their glucose and stress. The goal is to see if this approach is practical and worth testing in a larger t…
Phase: NA • Sponsor: State University of New York at Buffalo • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Nightshift sleep breakthrough? study tests CBT for shift work disorder
Knowledge-focused Recruiting nowThis study looks at whether a person's tendency to have trouble sleeping when stressed (called sleep reactivity) is a main cause of Shift Work Disorder. Researchers will reduce the mismatch between workers' body clocks and their nightshift schedule, then see if those with high sl…
Phase: NA • Sponsor: Henry Ford Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Night shift Workers' weight gain mystery under investigation
Knowledge-focused Recruiting nowThis study aims to understand why night shift work is linked to obesity. Researchers will compare 1000 night shift and day workers across five European countries, measuring body composition, diet, and biological markers like hormones and inflammation. The goal is to uncover the m…
Sponsor: University of Vienna • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:51 UTC