Do THC and CBN gummies hold the key to better sleep?

NCT ID NCT07769164

NEW Completed Symptom relief Sponsor: Cannabis Science Innovations, LLC Source: ClinicalTrials.gov ↗

First seen Aug 17, 2026 · Last updated Aug 17, 2026

Summary

This trial tests whether different combinations of cannabinoids—THC, CBN, CBG, CBD, and melatonin—taken as gummies can improve sleep quality in adults aged 21 to 55 who report poor sleep. Participants will be randomly assigned to receive one of several active gummy formulas or a placebo, and will track their sleep, daytime fatigue, and mood. The study aims to see which combination, if any, helps people fall asleep faster, stay asleep, and feel better during the day.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Cannabinoid gummies containing THC, CBN, CBG, CBD, and melatonin
What this could lead to: If effective, these gummies could offer a new option for improving sleep quality and reducing daytime fatigue in people with poor sleep.
What could go wrong: This is an early-stage trial, and results may not show a clear benefit over placebo. Cannabinoids can cause side effects like drowsiness or dizziness, and the right dose or combination is still uncertain.

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Conditions

The condition(s) this trial relates to.

insomnia Parasomnias sleep disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SLEEP DISTURBANCE SLEEP QUALITY

Contacts and locations

Locations

Cannabis Science Innovations, LLC

Sarasota, Florida, 34232, United States

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