Melatonin may boost brain and blood sugar health in teens with diabetes

NCT ID NCT07592442

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether taking a melatonin supplement (3 mg each night for 6 months) could improve sleep, thinking skills, and blood sugar control in 70 adolescents with type 1 diabetes. Half received melatonin and half received a placebo. The researchers measured changes in blood sugar time-in-range, sleep quality, and executive function (like focus and planning). The goal was to see if this simple hormone supplement could help manage some common diabetes-related challenges.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
melatonin (3 mg tablet once daily)
What this could lead to
If it works, melatonin could become a simple, low-cost add-on to help teens with type 1 diabetes sleep better, think more clearly, and manage blood sugar more effectively.
What could go wrong
This is a small, completed trial with only 70 participants. Melatonin is not a diabetes treatment on its own, and any benefits may be modest or not apply to all teens. Long-term effects are unknown.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ain shams university

    Cairo, Egypt

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