Sleep hormone melatonin tested as painkiller for chronic back pain
NCT ID NCT06476392
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether taking melatonin before bed can reduce pain and improve sleep in people with chronic low back pain and insomnia. About 220 adults aged 18 to 64 with back pain for at least 3 months and sleep problems took either melatonin or a placebo for several weeks. The goal was to see if this safe, widely available hormone could offer a better option than risky painkillers like opioids.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Pain Center, University Hospital Odense
Odense, Funen, 5000, Denmark
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