Can a sleep apnea machine match the gold standard in detecting breathing pauses?

NCT ID NCT06317077

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This study evaluates whether prismaLINE PAP devices accurately count breathing events (apneas and hypopneas) compared to the gold-standard polysomnography (PSG) in people with sleep apnea. Participants will use a full face mask during a titration night, where the device briefly lowers pressure to provoke breathing events. The goal is to see if the device's apnea-hypopnea index (AHI) matches the manually scored PSG, and to confirm the safety and performance of the device and mask.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
PAP therapy with subtherapeutic phases to provoke breathing events, using Löwenstein Medical full face masks
What this could lead to
If successful, this could confirm that prismaLINE devices reliably measure breathing events, potentially improving home monitoring of sleep apnea therapy.
What could go wrong
This is a small, early-stage device validation study, not a treatment trial. Results may not apply to other devices or mask types, and the induced breathing events may not reflect real-world conditions.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Krankenhaus Bethanien

    Solingen, North Rhine-Westphalia, 42699, Germany

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