Sleeping pill may boost CPAP use in patients with double trouble

NCT ID NCT06017921

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a 14-day course of the sleep medication eszopiclone could help people with both insomnia and obstructive sleep apnea use their CPAP machine more consistently. Sixty participants were randomly assigned to receive either eszopiclone or a placebo. The researchers measured CPAP use after 30 days and again after 6 months, along with sleep quality and anxiety levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

eszopiclone (a sleep medication)

What this could lead to

If it works, this could point toward a way to help people with both insomnia and sleep apnea stick with CPAP therapy, improving their sleep and health.

What could go wrong

This is a small, completed phase 4 trial with only 60 participants, so results may not apply to everyone. The sleep aid might not improve CPAP use long-term and could cause side effects like drowsiness.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

insomnia obstructive sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sleep Laboratory, Heart Institute, Pulmonary Division, Hospital das Clínicas da Universidade de São Paulo

    São Paulo, 55, Brazil