Can a new painkiller prevent breathing crises after surgery?
NCT ID NCT07753785
First seen Aug 10, 2026 · Last updated Aug 12, 2026 · Updated 2 times
Summary
This study looks at whether a newer opioid painkiller, oliceridine, is less likely than the standard sufentanil to cause breathing problems after surgery in people at high risk of obstructive sleep apnea. About 851 adults with known or suspected sleep apnea will receive one of the two drugs through a patient-controlled pump. The main goal is to see how often respiratory depression occurs within 24 hours after surgery, and whether oliceridine offers a safer option.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Oliceridine and sufentanil, two opioid painkillers given through a patient-controlled pump after surgery.
- What this could lead to
- If oliceridine proves safer, it could become a preferred painkiller for people with sleep apnea, reducing dangerous breathing complications after surgery.
- What could go wrong
- This is an observational study, not a randomized trial, so results may be biased. Also, oliceridine may not be widely available or may have other side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Peking University Fist Hospital
Beijing, 100034, China
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