POSTOPERATIVE ANALGESIA

This study compares two ways to dilute the numbing drug bupivacaine for a nerve block used during arm surgery. Researchers want to see if using sugar water (5% dextrose) instead of salt water (0.9% saline) affects how well and how long the block works. About 90 adults having elec…

This study looks at whether combining two types of nerve blocks can help people who have heart surgery use fewer strong painkillers (opioids) and recover better. About 90 adults having planned heart surgery will receive one of two nerve block combinations. Researchers will measur…

This study compares two painkillers given through a patient-controlled pump after brain surgery. The goal is to see if oliceridine causes less nausea than the standard drug sufentanil. 174 adults having surgery near the base of the skull will be randomly assigned to one of the tw…

This study compares two types of ultrasound-guided nerve blocks to see which provides better pain relief after colorectal surgery. Fifty adults scheduled for open colorectal surgery will receive either an erector spinae plane block or an oblique subcostal transversus abdominis pl…

This study compares three types of nerve blocks (paravertebral, intertransverse, and erector spinae plane) given before video-assisted lung surgery. Researchers will measure how much opioid painkiller patients need afterward and their pain scores. The goal is to find which block …

This study compares two types of nerve blocks—PENG block and lumbar erector spinae plane block—to see which one better controls pain after total hip replacement. Fifty-two adults undergoing hip replacement under spinal anesthesia will be randomly assigned to receive one of the tw…

This study compares two types of nerve blocks—the PENG block and the Deep Iliacus Plane Block—for pain relief during spinal anesthesia positioning and after hip fracture surgery. 75 adults aged 30-85 will receive one of the blocks plus standard pain medication. The goal is to see…

This study compares two types of nerve blocks (ESP block and TAP block) to see which one works better for pain relief after open appendix surgery. About 68 adults having this surgery will be randomly assigned to receive one of the two blocks. The main goal is to see which block r…

This study compares two types of ultrasound-guided nerve blocks—TAP block and transversalis fascia plane block—for controlling pain after laparoscopic surgery in children aged 6 months to 16 years. The goal is to see which block provides better pain relief, lasts longer, and redu…

This study tests whether a specific nerve block, called the serratus posterior superior intercostal plane block, can reduce pain and opioid use after minimally invasive heart bypass surgery. Sixty adults undergoing this surgery will be randomly assigned to receive either the nerv…

This study tests whether a long-acting numbing medicine (bupivacaine liposome) can provide better pain relief after lung surgery compared to standard numbing medicine. About 496 adults having a lung lobe removed will receive a nerve block before surgery. The goal is to reduce pai…

This study looks at whether a specific nerve block (erector spinae plane block) can help control pain after laparoscopic abdominal surgery. About 50 adults undergoing these surgeries will receive the block, and researchers will measure how long it takes before they need extra pai…

This study tests if a nerve block (TAP block) is as good as or better than an epidural for pain after major abdominal cancer surgery. About 50 adults having surgeries like stomach, colon, or liver removal will be randomly assigned to one of the two methods. The goal is to see whi…

This study tests whether giving a combination of two drugs (lidocaine and dexmedetomidine) during weight-loss surgery can reduce pain, inflammation, and cell stress afterward. About 104 adults having laparoscopic bariatric surgery will receive either the combo, one drug alone, or…

This study tests a new drug called HRS-2129 for managing pain after abdominal surgery. About 360 adults having abdominal surgery will receive either HRS-2129, a placebo, or the standard painkiller tramadol. The goal is to see if HRS-2129 works better or has fewer side effects tha…

This study compares two methods to reduce pain after laparoscopic hernia surgery: injecting anesthetic into the surgical area versus a nerve block (TAP block) guided by ultrasound. Sixty adults undergoing hernia repair will be randomly assigned to one of the two groups. Researche…

This study looks at whether an ultrasound-guided Quadro-Iliac Plane Block (QIPB) can reduce pain and opioid use after lumbar spinal surgery. Researchers will follow 60 adults undergoing elective surgery, comparing those who receive the block plus standard pain relief to those who…

This study watches 90 adults having open heart surgery to compare three standard pain relief methods: IV drugs, an epidural, or a nerve block. The main goal is to see which method best prevents chronic pain 3 months later. Researchers will also track pain levels, recovery speed, …