New painkiller aims to cut nausea after brain surgery
NCT ID NCT07479446
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two painkillers given through a patient-controlled pump after brain surgery. The goal is to see if oliceridine causes less nausea than the standard drug sufentanil. 174 adults having surgery near the base of the skull will be randomly assigned to one of the two drugs. Researchers will track nausea, pain levels, and other recovery measures for 48 hours after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Oliceridine
- What this could lead to
- If it works, this could point toward a painkiller that causes less nausea after brain surgery.
- What could go wrong
- This is a small, early-stage trial comparing two drugs, so results may not apply to all patients. Oliceridine might not reduce nausea as hoped, or could have other side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Xuanwu Hospital, Capital Medical University
RECRUITINGBeijing, China
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