New painkiller aims to cut nausea after brain surgery
NCT ID NCT07479446
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two painkillers given through a patient-controlled pump after brain surgery. The goal is to see if oliceridine causes less nausea than the standard drug sufentanil. 174 adults having surgery near the base of the skull will be randomly assigned to one of the two drugs. Researchers will track nausea, pain levels, and other recovery measures for 48 hours after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Oliceridine
What this could lead to
If it works, this could point toward a painkiller that causes less nausea after brain surgery.
What could go wrong
This is a small, early-stage trial comparing two drugs, so results may not apply to all patients. Oliceridine might not reduce nausea as hoped, or could have other side effects.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Xuanwu Hospital, Capital Medical University
RECRUITINGBeijing, China
Contact Phone: •••-•••-•••• Email: •••••@•••••