POSTOPERATIVE ANALGESIA

This study tests whether a long-acting numbing drug (liposomal bupivacaine) can reduce pain for up to 72 hours after open upper abdominal surgery. 148 adults having liver, stomach, or pancreatic surgery will get either the long-acting drug plus standard numbing, or standard numbi…

This study will test whether adding dexmedetomidine or clonidine to standard spinal anesthesia can reduce uncomfortable pulling, tugging, and pressure sensations during cesarean delivery. About 150 pregnant women having a C-section will be randomly assigned to receive one of the …

This study tests whether giving a combination of two drugs, dexmedetomidine and esketamine, during and after spinal surgery can reduce moderate-to-severe pain in the first three days after the operation. About 274 adults aged 40 to 80 having spine surgery will be randomly assigne…

This study tests whether giving a combination of two drugs (dexmedetomidine and esketamine) before and after spine surgery can lower the risk of long-term pain. About 274 adults aged 40-79 having spine surgery will take part. The goal is to see if this approach reduces pain that …

This study tests three different pain-blocking methods in 147 men having robotic prostate surgery. The goal is to see which method provides the best pain relief, reduces the need for strong painkillers, and helps patients recover faster. Participants will receive one of three tec…

This study tests whether spraying a local anesthetic into the chest cavity after lung surgery can reduce pain from drainage tubes. 300 adults having keyhole lung surgery will be randomly assigned to receive either one of two anesthetic sprays or a placebo. Pain levels, sleep qual…

This study compares two drug combinations given through an IV to manage pain after vaginal hysterectomy. 50 women will receive either dexmedetomidine alone or with ketamine. The goal is to see which provides better pain relief and reduces the need for extra painkillers in the fir…

This study will compare two types of nerve blocks for pain relief after knee arthroscopy. 72 adults scheduled for knee surgery will receive either an adductor canal block or a genicular nerve block, both combined with an IPACK block. The goal is to see which method delays the nee…

This study compares two medicines, morphine and dexmedetomidine, when added to a standard numbing drug for a nerve block after knee surgery. The goal is to see which combination provides longer pain relief. Fifteen adults undergoing knee surgery will take part.

This study compares two ways to numb the area for pain relief after circumcision in children: an ultrasound-guided penile block and a nerve-stimulation-guided pudendal block. Researchers want to see if the ultrasound method works just as well. About 240 children will take part to…