New drug cocktail aims to cut Post-Surgery pain in half

NCT ID NCT07523321

First seen Apr 14, 2026 · Last updated Jun 13, 2026 · Updated 8 times

Summary

This study tests whether giving a combination of two drugs, dexmedetomidine and esketamine, before and after spinal surgery can lower the chance of moderate-to-severe pain in the first three days after surgery. About 274 adults aged 40 to 79 having spine surgery will take part. The goal is to see if the combo works better than standard care for pain relief and also helps protect thinking and memory after surgery.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Peking University First Hospital

    Beijing, Beijing Municipality, 100034, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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