POSTOPERATIVE ANALGESIA

This study tests whether a long-acting painkiller (bupivacaine liposome) given as a nerve block can improve pain control and recovery after lung surgery. About 496 adults having a lung lobe removed will be randomly assigned to receive either the long-acting painkiller plus a stan…

This study compares two types of ultrasound-guided pain injections (TFPB and TAP block) in 36 children aged 6 months to 16 years having laparoscopic surgery. The goal is to see which injection provides better pain relief after surgery, how long the relief lasts, and whether child…

This study compares two types of nerve blocks—erector spinae plane block and lateral transversus abdominis plane block—for pain relief after open appendix removal. About 68 adults will receive one of the blocks before surgery, and researchers will measure how much morphine they n…

This study looks at whether a special ultrasound-guided nerve block (Quadro-Iliac Plane Block) can help control pain after lumbar spine surgery. About 60 adults having elective back surgery will be observed. The goal is to see if the block lowers pain scores and reduces the need …

This study compares two methods to reduce pain after laparoscopic hernia repair: injecting numbing medicine into the surgical area or using an ultrasound-guided nerve block (TAP block). Sixty adults having hernia surgery will be randomly assigned to one of the two groups. Researc…

This study compares two ways of mixing the numbing drug bupivacaine for a nerve block in the arm. One uses sugar water (D5W) and the other uses salt water (normal saline). Researchers want to see which mixture works faster, lasts longer, and provides better pain relief for people…

This study tests whether a specific nerve block, given before surgery, can reduce pain and the need for strong painkillers after minimally invasive heart bypass surgery. Sixty adults will be randomly assigned to receive either the nerve block plus standard care or standard care a…

This study compares two types of nerve blocks (PENG block and Deep Iliacus Plane Block) to see which provides better pain relief for people with hip fractures. The blocks are given before spinal anesthesia and after surgery. 75 adults aged 30-85 will take part. The goal is to fin…

This study tests whether giving a combination of two drugs (lidocaine and dexmedetomidine) during weight-loss surgery can reduce pain, inflammation, and cell stress afterward. About 104 adults having laparoscopic bariatric surgery will be randomly assigned to receive the combo, o…

This study tests two different doses of a pain medicine called ketorolac, given through a vein, to see which works better for pain after a planned C-section. About 126 women will take part and rate their pain on a 0-10 scale. The goal is to improve comfort right after delivery.

This study is testing a new medicine called HRS-2129 to see if it can safely reduce pain after abdominal surgery. About 360 adults having abdominal surgery will receive either HRS-2129 or a comparator drug. The main goal is to measure how much pain relief patients get during the …

This study looks at whether a specific nerve block, called the erector spinae plane block, can help control pain after laparoscopic abdominal surgery. Researchers will measure how long it takes for patients to need extra pain medicine and how much morphine they use. The study inv…

This study tests if a nerve block (TAP block) is as safe and effective as an epidural for pain relief after major abdominal cancer surgery. About 50 adults having surgeries like stomach or colon removal will be enrolled. The goal is to see which method reduces the need for extra …

This study looks at three common ways to manage pain after open heart surgery: IV pain medicine, an epidural, and a nerve block. The goal is to see which method helps prevent long-term pain that can last for months. Researchers will follow 90 adults for 3 months after surgery to …