Which pain block works best after colorectal surgery?
NCT ID NCT07602452
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two types of ultrasound-guided nerve blocks to see which provides better pain relief after colorectal surgery. Fifty adults scheduled for open colorectal surgery will receive either an erector spinae plane block or an oblique subcostal transversus abdominis plane block. Researchers will measure pain levels and how soon patients need extra pain medication.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- nerve block (local anesthetic injection)
- What this could lead to
- If one block works better, it could improve pain control after colorectal surgery and reduce the need for strong painkillers like morphine.
- What could go wrong
- This is a small, early-stage study with only 50 participants. Results may not apply to all patients, and nerve blocks carry risks like bleeding or infection.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2026
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 to 75 years old. * Both sexes. * American Society of Anesthesiologists (ASA) physical status II-III. * Scheduled for open colorectal surgery under general anesthesia. Exclusion Criteria: * History of opioid abuse. * Chronic opioid consumption. * Body mass index (BMI) ≥ 35 kg/m2. * Severe cardiac insufficiency, defined as New York Heart Association (NYHA) class III or IV heart failure. * Renal failure, defined as an estimated glomerular filtration rate (eGFR) \< 30 mL/min/1.73 m². * Hepatic encephalopathy. * Having a skin infection at or near the puncture site. * Coagulopathy, defined as platelet count \< 100,000/mm³, INR \> 1.5, or use of anticoagulant therapy that could not be withheld. * Allergy to drugs used in the study. * History of previous or recurrent laparoscopic cholecystectomy procedures.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Cairo University
RECRUITINGCairo, 12613, Egypt
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