COLORECTAL SURGERY

This study is testing a new monitoring tool called xBar to see if it can safely and effectively detect dangerous leaks (anastomotic leaks) after colorectal surgery. The study will enroll 190 adults having rectal or sigmoid surgery. The clinical team will not see the xBar results,…

This study tests whether placing a small mesh tube (stent) in a narrowed artery that supplies blood to the gut, done before planned colon surgery, can prevent a serious complication called anastomotic leakage (a leak where the colon is reconnected). The trial will enroll 360 adul…

This study tests a new approach to prevent a serious complication called anastomotic leakage after colorectal cancer surgery. About 110 adults having surgery for colorectal cancer will either get a temporary tube placed inside the bowel (endoscopic vacuum therapy) right after sur…

This study tests a device that warms and moistens the carbon dioxide gas used during laparoscopic (keyhole) surgery for colon or rectal tumors. The goal is to see if this reduces pain 24 hours after surgery, so patients need fewer strong painkillers. About 148 adults having color…

This study looks at whether removing a urinary catheter one day after colorectal surgery is as safe as the usual three days. The goal is to lower the chance of urinary tract infections and shorten hospital stays. About 176 adults having certain types of colorectal surgery will be…

This study compares standard pain relief (IV drugs plus wound numbing) to a combination of two nerve blocks (BAP and TAP) in 140 adults having minimally invasive left-sided colorectal surgery. The goal is to see if the nerve blocks lower pain intensity and reduce the need for opi…

This study tests a special care plan for people 65 and older who are having colorectal surgery. The goal is to see if this plan helps them recover better after leaving the hospital and reduces the chance of being readmitted. About 30 participants will take part to see if the prog…

This study looks at whether checking for leaks during colorectal cancer surgery can lower the chance of serious problems after the operation. About 264 adults having surgery for colorectal cancer will be randomly assigned to either receive a leak test or not. The main goal is to …

This study looks at whether a rapid, point-of-care CRP test can help predict anastomotic leaks after planned colorectal surgery. Anastomotic leaks are a serious complication where the surgical connection in the bowel leaks. The study will enroll 500 adults having elective colorec…

This study looks at whether a special nutritional drink taken for 7 days before colorectal surgery can change levels of certain amino acids in the blood. The goal is to understand how these supplements might help reduce inflammation and improve recovery. About 126 adults schedule…

This study looks at whether a 30-day remote monitoring program can reduce hospital readmissions after colorectal surgery. About 362 adults who had or will have colorectal surgery will be randomly assigned to either the remote monitoring group or standard discharge. The main goal …

This study looks at a tool called the IFEED score to better define postoperative ileus, a temporary stop in bowel function that happens in about 20% of colorectal surgeries. Researchers will check if this score matches how long patients stay in the hospital. About 161 adults havi…