New nerve block could slash opioid use after heart surgery

NCT ID NCT07412522

First seen Feb 17, 2026 · Last updated Jun 22, 2026 · Updated 17 times

Summary

This study tests whether a specific nerve block, called the serratus posterior superior intercostal plane block, can reduce pain and opioid use after minimally invasive heart bypass surgery. Sixty adults undergoing this surgery will be randomly assigned to receive either the nerve block with bupivacaine or standard anesthesia alone. The main goal is to see if the block improves overall recovery quality and reduces the need for painkillers.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Kosuyolu High Specialization Training and Research Hospital

    RECRUITING

    Istanbul, 34870, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bupivacaine

What this could lead to

If effective, this nerve block could become a standard way to manage pain after heart surgery, reducing reliance on opioids and speeding recovery.

What could go wrong

This is a small, early-stage study with only 60 participants. The block may not provide significant pain relief, and there are risks like bleeding or infection at the injection site.

Conditions

The condition(s) this trial relates to.

coronary artery disorder Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.