New nerve block could slash opioid use after heart surgery

NCT ID NCT07412522

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a specific nerve block, called the serratus posterior superior intercostal plane block, can reduce pain and opioid use after minimally invasive heart bypass surgery. Sixty adults undergoing this surgery will be randomly assigned to receive either the nerve block with bupivacaine or standard anesthesia alone. The main goal is to see if the block improves overall recovery quality and reduces the need for painkillers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
bupivacaine
What this could lead to
If effective, this nerve block could become a standard way to manage pain after heart surgery, reducing reliance on opioids and speeding recovery.
What could go wrong
This is a small, early-stage study with only 60 participants. The block may not provide significant pain relief, and there are risks like bleeding or infection at the injection site.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Kosuyolu High Specialization Training and Research Hospital

    RECRUITING

    Istanbul, 34870, Turkey (Türkiye)

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