POSTOPERATIVE ANALGESIA

This early-stage study tests a new drug called YZJ-4729 tartrate, given as an injection, to see if it is safe and how the body handles it. The trial involves healthy adults aged 18 to 45. Researchers will measure side effects, drug levels in the blood, and how the drug is process…

This study compared two painkillers, oliceridine and morphine, in 252 adults undergoing laparoscopic colorectal surgery. The goal was to see if oliceridine causes less nausea and vomiting after surgery. Patients used a pump to control their pain medicine for up to 3 days after th…

This study tested whether nalbuphine, a painkiller, works as well as morphine for pain after surgery. 289 adults having abdominal or orthopedic surgery received either drug through a pump they could control. Researchers measured pain intensity differences over 48 hours to compare…

This study tested three different nerve blocks to see which provides the best pain relief after total knee replacement. Sixty adults having knee surgery under general anesthesia received one of the blocks. The main goal was to measure how long it took before they needed extra pai…

This study tested two different doses of a painkiller called ketorolac given through an IV after cesarean delivery. 125 women having planned C-sections took part. The goal was to see which dose provides better pain relief as part of a standard pain management plan.

This study compared two types of nerve blocks—recto-intercostal and external oblique intercostal—for pain relief after laparoscopic gallbladder removal. Sixty adults having elective surgery received one of the two blocks. Researchers measured how much extra painkiller they needed…

This completed study looked at whether giving dexamethasone or ibuprofen through an IV before hand or forearm surgery could make the nerve block pain relief last longer. 79 adults were enrolled and received one of the two drugs before their procedure. Researchers also tracked nau…

This study looked at whether giving ibuprofen and paracetamol before laparoscopic hysterectomy surgery helps control pain afterward. 70 adults participated. Researchers measured pain scores, opioid use, and side effects like nausea during the first 24 hours after surgery.

This study looked at 60 women having planned cesarean deliveries to compare two pain relief methods: giving morphine through the spinal needle versus a numbing injection near the belly muscles. The main goal was to see how many women needed extra pain medicine in the first 24 hou…

This study tested two methods to control pain after a total abdominal hysterectomy: an ultrasound-guided nerve block (TFP block) and a spinal injection of morphine. Sixty women took part to see which approach provides longer-lasting pain relief and reduces the need for extra pain…

This study compared two types of nerve blocks (EXORA and QLB) to see which provides better pain relief after laparoscopic gallbladder removal. Eighty adults received one of the two blocks using the numbing medicine bupivacaine. Researchers measured how long until patients needed …

This study tested two different ultrasound-guided nerve blocks to control pain after video-assisted chest surgery. 70 adults were randomly assigned to receive either an edge of laminar block or an erector spinae plane block. The goal was to see which block reduces the need for mo…

This study tested whether a specific nerve block (EXORA) can reduce pain and the need for morphine after umbilical hernia repair. Fifty adults were randomly assigned to receive either the nerve block with a numbing medicine or a sham injection. The main goal was to see how much m…

This study tested two types of ultrasound-guided nerve blocks for pain control after open kidney surgery. 70 adults received either a subtransverse interligamentary block or a thoracic paravertebral block with bupivacaine. Researchers measured how much morphine patients needed an…

This study looked at 117 women having planned C-sections to compare two pain relief methods: morphine given during spinal anesthesia and a nerve block (ultrasound-guided transversalis fascia plane block). Researchers measured pain levels, how long until patients needed extra pain…

This study tested two different nerve block techniques to see which provides better pain relief after septorhinoplasty (nose surgery). 93 adults aged 18-65 were randomly assigned to receive one of the two blocks. Researchers measured pain scores, agitation, and side effects to fi…

This study looked at 60 adults having heart bypass surgery to compare two types of chest wall nerve blocks for pain control. One group got a combination of two blocks, the other got a different pair. Researchers measured pain scores and how much extra pain medicine patients neede…

This study compared two types of nerve blocks for pain after laparoscopic gallbladder removal. Sixty adults received either an erector spinae plane block or a subcostal transversus abdominis plane block using the same numbing medicine. Researchers measured pain levels, need for e…

This study tested two ways to numb pain after hypospadias repair in 30 boys aged 1-8 years. One group got a shot near the tailbone (caudal block), the other near the penis (dorsal penile block). The caudal block worked better for the first few hours and reduced the need for extra…

This study tested two different pain-relief methods for children aged 1 to 7 having hernia surgery. One method uses an ultrasound to guide a numbing injection near the belly muscles, while the other is a standard injection near the tailbone. The goal was to see which one keeps ch…

This study compared two types of nerve blocks (EOIP block and TAP block) for pain control after open kidney surgery in 40 adults. The goal was to see which block reduces the need for extra pain medicine and improves comfort. Results help doctors choose the best option for postope…

This study tested two different ultrasound-guided nerve blocks to control pain in 40 children after open kidney surgery. The goal was to see which block delayed the need for extra morphine and reduced overall pain medicine use. Results help doctors choose the best pain control me…

This study tested whether adding dexmedetomidine to a standard local anesthetic (bupivacaine) in a nerve block after C-section can improve pain relief. 80 women having planned C-sections took part. The goal was to see if the combination extends pain-free time, reduces recovery ti…