New painkiller nalbuphine takes on morphine in Post-Surgery trial
NCT ID NCT06949852
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether nalbuphine, a painkiller, works as well as morphine for pain after surgery. 289 adults having abdominal or orthopedic surgery received either drug through a pump they could control. Researchers measured pain intensity differences over 48 hours to compare effectiveness and safety.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Nalbuphine (a painkiller)
- What this could lead to
- If it works, this could offer a new option for managing pain after surgery with possibly fewer side effects than morphine.
- What could go wrong
- This is a completed Phase 3 trial, but results are not yet published. Nalbuphine may not be more effective or safer than morphine for all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for POSTOPERATIVE ANALGESIA are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Affiliated Hospital of Jiangnan University
Wuxi, China
-
Cangzhou People's Hospital
Cangzhou, China
-
Chengdu Fifth People's Hospital
Chengdu, China
-
Chongqing University Affiliated Fuling Central Hospital
Chongqing, China
-
Deyang People's Hospital
Deyang, China
-
Heping Hospital affiliated to Changzhi Medical College
Changzhi, China
-
Liuzhou Worker's Hospital
Liuzhou, China
-
Mianyang Central Hospital
Mianyang, China
-
Nanjing Drum Tower Hospital
Nanjing, China
-
Ningbo Medical Center LIHUILI Hospital
Ningbo, China
-
Ningbo NO.2 Hospital
Ningbo, China
-
Peking University First Hospital
Beijing, China
-
Shanxi Bethune Hospital
Taiyuan, China
-
Sichuan Provincial People's Hospital
Chengdu, China
-
The First Affiliated Hospital Of University Of South China
Hengyang, China
-
The First Affiliated Hospital of Fujian Medical University
Fuzhou, China
-
The First Affiliated Hospital of Jinan University
Guangzhou, China
-
The First Affiliated Hospital of Wannan Medical College
Wuhu, China
-
The First People's Hospital of Changde City
Changde, China
-
The First People's Hospital of Lianyungang
Lianyungang, China
-
The Second Affiliated Hospital of Jiaxing University
Jiaxing, China
-
The Second Nanning People's Hospital
Nanning, China
-
The Third Xiangya Hospital of Central South Univerdity
Changsha, China
-
Xi'an Honghui Hospital
Xi'an, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Which nerve block wins for hip surgery pain?
- Which painkiller wins after hysterectomy? a Head-to-Head test
- Can a new painkiller prevent breathing crises after surgery?
- Which nerve block eases circumcision pain best? a Head-to-Head trial
- New Long-Acting anesthetic could mean fewer pain shots after surgery
- Which pain block works best after hysterectomy? ultrasound, surgical, or local injection?